When comparing Elixir vs Pharo, the Slant community recommends Elixir for most people. In the question“What is the best programming language to learn first?” Elixir is ranked 9th while Pharo is ranked 20th. The most important reason people chose Elixir is:
Leverages the existing Erlang BEAM VM
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Great for concurrency
Leverages the existing Erlang BEAM VM

Pro Great getting started tutorials
The tutorials are very clear and concise (even for a person not used to functional programming). Plus they are also very mobile friendly.
Pro Powerful metaprogramming
Write code that writes code with Elixir macros. Macros make metaprogramming possible and define the language itself.
Pro Full access to Erlang functions
You can call Erlang functions directly without any overhead: https://elixir-lang.org/getting-started/erlang-libraries.html
Pro Scalability
Elixir programming is ideal for applications that have many users or are actively growing their audience. Elixir can easily cope with much traffic without extra costs for additional servers.
More details can be found here.
Pro Great as a first functional programming language!

Pro Great documentation
Elixir's documentation is very good. It covers everything and always helps solving any problem you may have. It's also always available from the terminal.

Pro Syntax is similar to Ruby, making it familiar for people used to OOP
All of the benefits of Erlang; without as steep a learning curve of prolog based syntax. Elixir is heavily inspired by Ruby's syntax which many people love.

Pro Easy to download libraries
Comes with built in build tool called "mix". This will automatically download libraries and put them in the scope of the application when you add them to the "deps" function and run mix deps.get
Pro Object-Oriented
In Pharo everything is an object. Compiler - object, network - object, method - also an object. And objects communicate with messages. No operators, no control-flow statements. Just objects and messages. Few things to learn, but you can learn OOP well.
Pro Easily learnt
There is good, free documentation including several books written by experts with extensive examples. There is an online MOOC. There are many tutorial videos. Supportive conferences and community. Even a professional support option if desired.
Pro Live updates
The nature of Pharo being a "live" environment allows you to perform live updates to your system without requiring to restart it. You can upgrade/modify classes while serving requests at the same time.
Pro Highly productive
Pro Seaside
The framework for developing sophisticated web applications in Smalltalk is developed in Pharo. Seaside lets you build highly interactive web applications quickly, reusably and maintainably.
Pro Remote debugging
Pro Beautiful coding patterns in your IDE
No need to search google for compact beautiful examples of how to do things, your live environment source is available and you can easily live search, see how it works and copy how the masters would do it (examples most languages still copy too).
Pro Glamorous toolkit & GTInspector
Most languages are still copying the Smalltalk tools of yesterday - GTInspector (written in Glamorous) takes live exploration of code/running objects to a new level. It's really slick, and better yet, you can easily write your own inspectors in 10 lines of code.
Pro Code can be run on rock solid GemStone environment
Pro 64 bit support as of Pharo 7
Use 32 bit or 64 bit versions of Pharo on Windows, Mac & Linux.
Pro Advanced code analysis tools
MOOSE environment provides extensive, easily leveraged and class leading tools for code analysis and improvement.
Pro Can run headless for production
Pro Really simple networking and REST with Zinc
Pro Graphics, graphing and visualisation framework - Roassal
Roassal and Mondrian provide fantastic and easily used frameworks for graphics, graphing and advanced visualisations (comparable to D3.js) but with much less code. Visualisations can be rendered into web friendly graphics (SVG, .png etc.) without additional work.
Cons
Con Deployment is still not as easy as it should be
Con Some design choices may seem strange
Some design choices could have been a little more appealing, for example: using "do...end" comes natural in Ruby for blocks but Elixir uses them for everything and it looks pretty weird:
Enum.map [1, 2, 3], fn(x) -> x * 2 end
or
receive do
{:hello, msg} -> msg
{:world, msg} -> "won't match"
end
Con Small community
But they are very friendly and supportive. Best help comes through the mailing lists so not always easily googlable. There is also a Slack community where help is nearly instantaneous.
Con Odd language
Requires a different mindset. Much harder to apply what you know from popular or conventional languages . Switching over from or between other languages is more difficult.
Con Single threaded
Pharo's VM only ever uses one CPU core. If you want to write code that uses more than one CPU core, you need to jump through hoops such as running multiple VMs and synchronising your data.
