When comparing Spring-boot vs Pyramid, the Slant community recommends Spring-boot for most people. In the question“What are the best backend web frameworks?” Spring-boot is ranked 9th while Pyramid is ranked 15th. The most important reason people chose Spring-boot is:
Boot is just a thin configuration layer over Spring Framework, as such it inherits all the strengths of Spring.
Specs
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Pros

Pro Inherits all of Spring's strengths
Boot is just a thin configuration layer over Spring Framework, as such it inherits all the strengths of Spring.

Pro Preconfigured starters

Pro Fast prototyping
Spring boot is built for fast prototyping.

Pro Kick down to Spring
Pro Very flexible
Pyramid can be used for creating small applications quickly and easily, but it also powers up large enterprise-scale applications such as Dropbox.
Pro Persistence agnostic
Either NoSQL and SQL (including SQLAlchemy plugin).
Pro Comes with security included
Includes authorization and authentication with multiple backends.
Cons
Con Lacking in UI development
While actually very good and with a very complete and rich feature set to develop and maintain code on the server side, it still doesn't provide any rich framework for building good user interfaces.
Con The great number of options it offers can become intimidating
One of Pyramid's greatest drawbacks is that it requires a lot of set up in the beginning of a project. This can feel overwhelming and can keep people away from using it.
