When comparing pkgsrc vs Backblaze, the Slant community recommends Backblaze for most people. In the question“What are the best power user tools for macOS?” Backblaze is ranked 10th while pkgsrc is ranked 62nd. The most important reason people chose Backblaze is:
The default configuration includes everything except for system files to be backed up. That also includes external USB drives. This will work for most people. It can, of course, be customized to each person's liking.
Specs
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Pros
Pro pkgin is an apt-like tools for installing binaries from pkgsrc
pkgin aims to be a tool similar to apt/yum for managing pkgsrc binaries by relying on pkg_summary for installing, removing and upgrading packages and dependencies, using a remote repo.
Pro Adapted for use on over a dozen different operating systems
Has been adopted to be used on several Unix-like operating systems and Windows. It's also the default package manager of DragonflyBSD and of the (now discounted) Bluewall Linux distro.
Pro Installs and works in the same way as MacPorts
Installs its own dependencies which means that it is very secure. Cannot install anything unless you use the "sudo" command which is in keeping with the Unix philosophy.
Pro Both binary packages and source build possible
Fast software installation is possible by using binary packages. It's also easy to build from source which allows for different compile-time options (like different UI backends) as well as gaining access to pre-release versions of software in certain cases.
Pro Offering tooling for backporting fixes
Backporting fixes can be done by cherry-picking updates from a newer branch (pkgsrc is released every 3 months) and creating a package. Sometimes bugs need to be fixed for production and there is neither a fix in newer pkgsrc nor the softwares upstream. So pkgsrc has tools like pkgdiff, mkpatches, etc. that help with developing patches and building binary packages from that. A bit of documentation about that process can be found here.
Pro Does not need Xcode command line tools or Xcode.
This means that you can install it fresh on a new installation of MacOS and have all your favorite apps installed right from the start.
Pro Works easily with Ansible
Can be used from within Ansible to install packages on macOS.
Pro Easy installation if you use 3rd party scripts
This one works brilliantly.
Pro Beginner-friendly defaults
The default configuration includes everything except for system files to be backed up. That also includes external USB drives. This will work for most people. It can, of course, be customized to each person's liking.
Pro No file size or traffic restrictions
There are no limitations of file size or amount of data you can upload. The $5/mo plan gets you unlimited cloud storage.
Pro Excellent restoration performance
Backblaze creates a zip file of all your files for you to download, thus decreasing the amount of data you need to download and increasing the speed of the download since it's one connection instead of multiple that need to be opened and closed for a list of files.
Pro Secure
AES encrypted files are transferred over a secure SSL connection.
Pro Download any backed-up files from any web browser
Some backup services like Carbonite require a client to be installed to restore files. Backblaze allows you to login and download any or all files from a web browser, meaning it also serves as an ad-hoc cloud storage platform.
Pro Users can order a physical copy of their data
You can have a flash drive or an external hard drive delivered to you. They cost $99 and $189 respectively.
Cons
Con Relatively complicated setup and installation
Installing and setting pkgsrc up is a bit more complicated than in other package managers where it often consists in running a single script.
Con Not so broadly used on MacOS as compared with MacPorts
You do not hear about Pkgsrc as openly as you hear the words "HomeBrew" or "MacPorts".
Con Outdated packages
Some packages are outdated.
Con Can't install some packages
Even building well known packages (except MacPorts) from source using the ports can fail.
Con No Linux support
There's no Linux client for Backblaze.
Con Pay extra to keep deleted files permanently
Additional $2/Month plus $0.005/GB/Month for files updated, changed, or deleted more than one year ago.
Con Backblaze does not support network (NAS) drives
If you use a thing like Drobo, Backblaze will not back it up.