When comparing Hy vs CMUCL, the Slant community recommends Hy for most people. In the question“What are the best Lisp dialects?” Hy is ranked 8th while CMUCL is ranked 13th. The most important reason people chose Hy is:
Hy compiles to Python's abstract syntax trees. Python can import Hy modules, and Hy can import Python modules.
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Pros
Pro Python interop
Hy compiles to Python's abstract syntax trees. Python can import Hy modules, and Hy can import Python modules.
Pro Easier to read
Distinguished between arrays (or vectors) and function calls by using [] and (), respectively.
Pro Copyfree and open source
Uses the MIT (expat) license.
Pro Fast execution, faster compilation
CMUCL runs about as fast as SBCL, and they are both among the fastest Common Lisp implementations. CMUCL compiles faster than SBCL, cutting down on development, deployment, installation, and user testing turnaround time.
Pro Stand-alone executables
Pro Copyfree licensed (revised BSD license)
Most of CMUCL is in the public domain, with a few subsytems under permissive license.