When comparing Tessel 2 vs esp32, the Slant community recommends Tessel 2 for most people. In the question“What are the best single-board computers?” Tessel 2 is ranked 36th while esp32 is ranked 45th. The most important reason people chose Tessel 2 is:
Out of the box it supports Node 4.x LTS and doesn't require any setup to use it.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro NodeJS support out of the box
Out of the box it supports Node 4.x LTS and doesn't require any setup to use it.
Pro Co-processor system
Runs Linux and user application code on a 580MHz Mediatek router-on-a-chip, with an asynchronous 48MHz SAMD21 coprocessor for GPIO, ADC, I2C, SPI, PWM and UART programming
Pro Programmable via USB or Wifi
The process for deploying software, whether it's JavaScript, Python or Rust, is exposed the same way for both USB and Wifi connections.
Pro Easy to get started with
The Tessel 2's "Getting Started" experience requires little more than installing Node.js and a single package (the CLI) via npm. Complete walkthroughs for Linux, Mac and Windows are available and up-to-date
Pro Many variants available
Many different variants are available depending how good you are at soldering or how small it needs to be.
Pro Very small
Can fit inside small devices.
Pro Very cheap
Without case can be below $5.
Pro Has ultra-low power mode
Pro Has bluetooth and wifi modules
Cons
Con Very little memory
64 megabytes of RAM. This places it more in line with an Arduino style board than a SBC on the level of Raspberry Pi.
Con Some variants require soldering
Not all variants include easily plugable pins. Usually only the more expensive variants include these.