When comparing AppCleaner vs Transmit 4, the Slant community recommends Transmit 4 for most people. In the question“What are the best power user tools for macOS?” Transmit 4 is ranked 4th while AppCleaner is ranked 6th. The most important reason people chose Transmit 4 is:
Exchange data with FTP, SFTP or WebDAV servers or your Amazon S3 storage.
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Pros
Pro Easily and properly uninstall apps without leaving bits and pieces behind
Pro Saves a lot of room and cleans up your hard drive
AppCleaner does a much more thorough job removing unwanted applicated compared to the default method. This saves space and potentially speeds up your Mac.
Pro Simple, drag'n'drop app deletion
Pro Can whitelist certain apps
Pro Uninstalls widgets and plug-ins as well
Pro Fast and powerful file exchange client
Exchange data with FTP, SFTP or WebDAV servers or your Amazon S3 storage.
Pro Supports Amazon S3 & WebDAV
In addition to FTP, allows exchanging data with SFTP or WebDAV servers or your Amazon S3 storage.
Pro Enable a server connection as a normal disk in your Finder
So you can access your storage without the Transmit client.
Pro FTP Sync
Scans local and remote for difference and only transfer modified files. It's not rsync, but it's the next best thing
Pro Can enable a server connection as a normal disk in your Finder
So you can access your storage without the Transmit client.
Cons
Con Closed-source
No source available. No open source license.