When comparing Topcoat vs pico, the Slant community recommends Topcoat for most people. In the question“What are the best minimal CSS frameworks?” Topcoat is ranked 19th while pico is ranked 27th. The most important reason people chose Topcoat is:
Every Topcoat component is built with performance in mind. Most of the stylesheets are small and do not take too long to load.
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Pros
Pro Focused on performance
Every Topcoat component is built with performance in mind. Most of the stylesheets are small and do not take too long to load.
Pro Built-in cheat sheet for shortcuts
All command characters are shown at the bottom of the editor.
Pro Easy to use
Pico includes only the bare minimum of functionality needed to edit documents making it very simple.
Cons
Con Not so impressive design
But it is themeable.
Con Some issues with typography
For some components the text size is quite small, while for others it's too light over a light background, making the text harder to read.
Con No way to override command characters
Characters such as ^D, ^T, ^L, etc will always be interpreted as commands and there's no way to write them in text.
Con Lacks some commonly expected functionality even for a basic editor
Pico lacks search and replace functionality as well as the ability to work work with multiple files at the same time.