When comparing PySide vs MD Python Designer, the Slant community recommends PySide for most people. In the question“What are the best Python GUI frameworks/toolkits?” PySide is ranked 7th while MD Python Designer is ranked 15th. The most important reason people chose PySide is:
Qt for Python aka PySide2 is the official set of Python bindings supported by the Qt Company.
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Pros
Pro Supported by the Qt Company
Qt for Python aka PySide2 is the official set of Python bindings supported by the Qt Company.
Pro Qt widgets
Possibility to use a traditional widget-based user interface.
Pro QtQuick/QML
Possibility to use a declarative approach to define the user interface.
Pro Weak copyleft
PySide is licensed under the LGPL, which makes it easier to incorporate into commercial projects than PyQt.
Pro Amazing array of uses
The GUI Designer is compatible with all the features of the software. It is compatible with all major databases. They have an interesting GUI database form on their webpage. The GUI can also include graphs and you can create applications like desmos. You can also use ICP DAS, LabJack and Advantech devices.
Pro No adjustment required
The GUI designer has more than one coding language that it's compatible with, however it works well with Python. The transition from Kivy is easy.The GUI Designer is super easy to use and saves lots of time.
Cons
Con Similar to PyQt, you need a C++ background. at least you can read C++ code
Qt's document is poor, and Qt for Python(PySdie) is even worse. this document assumes that you are already familiar with Qt. if you want to customize a Widget, you need to look at the Qt C++ source code to know what to do.
Con Visual appearance compared to other GUI frameworks/Designers
The end product did not look as appealing as it would have done with a different GUI Designer. However, it still looked professional and got the job done perfectly.