When comparing Spine vs Pyxel Edit, the Slant community recommends Spine for most people. In the question“What are the best 2D animation tools for game development?” Spine is ranked 3rd while Pyxel Edit is ranked 5th. The most important reason people chose Spine is:
Ranked in these QuestionsQuestion Ranking
Pro Integration libraries support most engines
Pro Simplified UI allows for an easy learning curve
No-nonsense workflow allows you to create your artwork in programs much better suited for the task like Illustrator and Inkscape for example, while Spine itself focuses only on the important task of skeletal animation.
Pro Allows for easy use of artwork from third party programs
Spine's developers provide scripts which makes exporting artwork from third party programs much easier to do.
Pro Community-driven feature roadmap
Esoteric Software maintains public Trello boards to help plan and prioritize feature additions.
Pro Funded via Kickstarter
Spine received resounding support from Kickstarter backers, beating its pledge goal by over 5 times.
Pro Intuitive UI
Pyxel Edit is widely acclaimed for its ease of use.
Pro Supports animations
Tiles can be animated within Pyxel Edit, with "onion skin" frame overlays to assist in making smooth frame transitions.
Pro Tileset extraction
Given an image and specified tile dimensions, Pyxel Edit will extract a tileset with no duplicate tiles. This mostly works for flat images though. If you feed Pyxel "finished maps" you will still get a lot of duplicates.
Pro Tilemap serialization support
Tile-based images (maps) built in Pyxel Edit can be serialized via XML or JSON for easy import elsewhere.
Pro Cheap compared to others
For only $9 (£6), this is one of the cheapest but also one of the best pixel editors out there.
Pro Live tile-update
Instantly see if your tiles are tileable and/or seamless and fix it easily.
Con Professional Edition is expensive
Essential edition includes nearly all features, but IK Weights and Mesh Animations are not included in the Essential Edition.
Con No integration for some major engines
Spine does not directly support several popular 2D engines, including Construct 2, Clickteam Fusion, and GameMaker Studio. Unreal Engine and CryEngine also have no native modules.
Con Mac version is dependent on Adobe Air
The OSX version of the application requires Adobe Air to run.
Con Free version lacks features
The free version of Pyxel Edit is an outdated beta. It does not receive updates.
Con No Linux version
There is no Linux version of the editor.