When comparing Demina vs Marionette Studio, the Slant community recommends Marionette Studio for most people. In the question“What are the best 2D skeletal animation tools?” Marionette Studio is ranked 13th while Demina is ranked 14th. The most important reason people chose Marionette Studio is:
Marionette Studio team is actively involved in the development of this software. There is a changelog available and a public Trello board.
Ranked in these QuestionsQuestion Ranking
Pros

Pro Straightforward tutorials
Denima's user interface is very simple, and the primary documentation is a simple walk-through of the workflow.


Pro Open source
Demina is a C#/XNA application hosted on CodePlex under the Microsoft Public License.
Pro Actively maintained
Marionette Studio team is actively involved in the development of this software. There is a changelog available and a public Trello board.
Pro Cloud based solution
Projects and files can be stored in cloud and the is no need for creating backups.
Pro Animation export
Animations can be exported as image packs and using some 3rd party tools can be imported and used in Unity.
Pro Easy to use
Can be used by anyone - intuitive interface and short learning curve.
Pro Web-based software
Easy to be accessed as no software needs to be download or installed on your computer.
Cons

Con No longer under development
The most recent update to Denima occurred in October 2012.

Con XNA-specific
Denima's runtime library is intended to integrate with the XNA framework, which has been unsupported since April 2014.
Con It's not free
Con No integration for major game development engines
There is no integration with major game engines such as Unity, Construct 2D, Unreal, Cocos 2dx, etc.
