When comparing Demina vs Moho 12, the Slant community recommends Moho 12 for most people. In the question“What are the best 2D skeletal animation tools?” Moho 12 is ranked 8th while Demina is ranked 14th. The most important reason people chose Moho 12 is:
Cheaper than Toon Boom and Adobe Products. People often complain about the price hike, but the pro version does go on sale, and even the full priced version is less than other insdurty standards on the market.
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Pros

Pro Straightforward tutorials
Denima's user interface is very simple, and the primary documentation is a simple walk-through of the workflow.


Pro Open source
Demina is a C#/XNA application hosted on CodePlex under the Microsoft Public License.
Pro Cheaper than Toon Boom and Adobe Products
Cheaper than Toon Boom and Adobe Products. People often complain about the price hike, but the pro version does go on sale, and even the full priced version is less than other insdurty standards on the market.
Pro Good community support
Lots of online forums, Facebook groups, YouTube videos, etc.
Pro It's better than any 2D animation software on the market for vector based animations
It beats Adobe Flash and Toon Boom at vector based animation. It has more features for 2D vector animations with it's integration with 3D mesh and bone rigs. Smart bone rigs create better animtions with less distortions then Toon Boom, and there are no bone rig animation options with Adobe Flash.
Pro Easy to use interface
Quicker to animate and use than other similar products.
Cons

Con No longer under development
The most recent update to Denima occurred in October 2012.

Con XNA-specific
Denima's runtime library is intended to integrate with the XNA framework, which has been unsupported since April 2014.
Con Too expensive
Con Limited support for game engines
In most cases you'll have to export and edit sprite sheets. This will consume memory. Also, FBX file support is limited and not all features will run in Unity. Aside from Unity, there is no support for runtimes for video game engines. Also, many animation features such as vector integrated features will not export to Unity. Spriter, Spine, and Dragon Bones would be better options.
