When comparing Trillian vs Adium, the Slant community recommends Adium for most people. In the question“What are the best unified messenger apps?” Adium is ranked 2nd while Trillian is ranked 9th.
Ranked in these QuestionsQuestion Ranking
Pro In-house server support
You can set up a dedicated server to hold your communications. Great for businesses that want to build their own infrastructure.
Pro Multiple networks in one place
Among them Yahoo!, Facebook, Skype, Google, AIM, ICQ, XMPP, MSN. You can have multiple accounts associated with each service.
Pro Group chat
Trillian to Trillian group chat is available.
Pro Easy-to-use interface
Pro Supports file transfers
Pro Open source
Pro OTR encryption
Con Supports all dead services.
Con Appears to be abandoned
Not Gatekeeper-compatible, SSL cert expired, social media presence is ancient.
Con Lack of OMEMO encryption
the de facto standard for Jabber Texting [xmpp]
Con Release version has old OTR
The current release, version 220.127.116.11 only does OTR version 2, and version 3 has been out for a long time.
Con Lack of multi-resource message capability
No carbon copy, for example.
Con No antispam (built-in or by plugin)
It has no challenge-like antispam (such as seen on github.com/jesobreira/box-sentry plugin for pidgin).