When comparing Signal vs Antox, the Slant community recommends Signal for most people. In the question“What are the best messaging apps for Android?” Signal is ranked 1st while Antox is ranked 28th. The most important reason people chose Signal is:
Signal uses an advanced end to end encryption protocol that provides privacy for every message every time.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Provides security and privacy
Signal uses an advanced end to end encryption protocol that provides privacy for every message every time.
Pro Free and open source
Signal is free and open source software, enabling anyone to verify its security by auditing the code. It's the only private messenger that uses open source, peer-reviewed cryptographic protocols to keep your messages safe.
Pro Supports encrypted group chats
Pro Has a desktop app
Signal Desktop can be used on multiple devices and has most features of the Android version, although it still requires you to register with your phone.
Pro Supports sharing of various different media types
Signal supports: emoji, pictures, videos, audio, contacts, any location and GIF.
Pro Note to Self feature
Allows you to "send: messages to yourself and sync to desktop so you can use Signal as a kind of encrypted Pushbullet alternative
Pro You can easily view all media exchanged
You can easily view all media shared in the chat without scrolling back to when it was shared.
Pro Annonymous Sender (Encrypted)
The sender credentials can be encrypted with the rest of the message, leaving only the recipient address readable by the Signal server. Even if Signal wanted they couldn't see who is talking with who by this mean.
Pro Works everywhere in every country
Unlike most messenger apps, Signal works reliably in all countries by securely circumventing internet censorship.
Pro Recommended by Edward Snowden
Edward Snowden uses this messenger and recommends it to everyone who is concerned about his privacy.

Pro Free, open source
Antox is licensed under Creative Commons with source code available on GitHub. Being open source makes it possible to make sure your messaging are not controlled by a corporation.

Pro Peer-to-peer
There is no middleman, all communication happens between the users.
Cons
Con Needs access to your phone number and contacts to work
Con Single device
Signal can only be registered to one mobile device at a time. But you can link Signal to Signal Desktop.
Con Servers hosted in the US
A security risk due to National Security letters, which require giving up data to the US state, and making it illegal to disclose that.
Con Unreliable notifications
Sometimes messages won't be received if the Signal app has been closed for a long time or hasn't been opened after booting the device.
Con High data usage
Antox uses the Tox protocol which is Peer to Peer, so there will be high data usage and battery drain. WiFi only mode is currently recommended for now.
Con Still in early development
Antox is still really early in development, being in beta currently.
Con Battery drain
Antox uses the Tox protocol which is Peer to Peer, so there will be high data usage and battery drain.
