When comparing Polynote vs Zettlr, the Slant community recommends Zettlr for most people. In the question“What is the best cross-platform note-taking app?” Zettlr is ranked 49th while Polynote is ranked 59th. The most important reason people chose Zettlr is:
While many Markdown editors don't offer specific support for a certain type of workflow, or offer features for scientific workflows only, Zettlr offers features that help the writing process of journalists or researchers in the arts and humanities. It's a lot more text-focused than most editors.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Real-time collaborative
Multiple users can edit a note simultaneously, in real time.
Pro Minimal interface
The application is simple and fast. Can create, share and organize notes and notebooks on the same page.
Pro Focuses on writers
While many Markdown editors don't offer specific support for a certain type of workflow, or offer features for scientific workflows only, Zettlr offers features that help the writing process of journalists or researchers in the arts and humanities. It's a lot more text-focused than most editors.
Pro Citation support
While it supports a diverse range of syntax (chart, easy image insert, etc.) found in other editors, the great citation support made it possible to write real articles. Citation from Zotero and Mendeley can be inserted easily which is a huge plus.
Pro Almost perfect
This is the best option, still not perfect, there are some bugs like creating / editing tables and resizing images, but the PROS destroy the CONS, easy quotes, WYSIWYM , attachments tab (supports attaching and opening links to any file), table of contents, TAGs, easy hyperlink between files (same as citations), export to many formats (like Word, HTML5, PDF)...
Pro Renders math in-place through KaTex
Cons

Con No free tier
Plynote has a 15-day free trial after which it requires a 20$/user/year subscription.
Con Obtrusive, like someone WITH CAPS LOCK ON
Too loud, too much going on, and definitely an in-your-face sort of feeling.
Con Large, slow, can't open just a single .md file
