When comparing pyglet vs Buildbox, the Slant community recommends pyglet for most people. In the question“What are the best 2D game engines?” pyglet is ranked 43rd while Buildbox is ranked 51st. The most important reason people chose pyglet is:
Since pyglet is so tightly woven with OpenGL it allows the support of drawing in 3D.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro 3D support
Since pyglet is so tightly woven with OpenGL it allows the support of drawing in 3D.
Pro Cross-platform
Works with Windows, Linux, and OS X.
Pro Written in pure Python
A small advantage, but being a core Python developer, it may be the best to stick to the roots and develop with pyglet as it is able to compile using other Python interpreters.

Pro Drag - and - drop editor
Drag - and - drop editor without writing any line of code.
Pro Easy to learn
Buildbox is a drag and drop engine, making it easy for beginners to pick up. There are many tutorials available to help get you started.
Pro Has many game templates
Buildbox has 20+ different game templates including templates for platformers, racing games and Flappy Bird clones.
Pro Built-in support for ads
You can add banner and interstitial ads from multiple ad networks, including AdMob, RevMob, Facebook. They can work with Amazon's, Microsoft's, Google's and Apple's app stores.
Pro Develop once publish everywhere
Exporting iOS/Android/macOS/Windows/Steam/Amazon
Pro Cross-platform
Cons
Con Small community/popularity
There is a decent amount of documentation and API to go along with pyglet, but in terms of community support there seems to be very little.
Con Incredibly Expensive
$99/mo for full functionality probably makes this the least accessible piece of game development software in regards to price, all with a very limiting feature set.
Con You are restricted by it's limitations
For example, you can only make certain kind of games.
Con Not very powerful
You will be limited to using templates to build games.
Con Subscription Model
The two more reasonable price points limit the functionality of a software already far less powerful than many more cost effective alternatives.

Con Very expensive
Buildbox has a 15-day trial version, after that a $2675 license to use it must be bought.
Con Stability Issues
The software has stability issues on Windows, with the preview window causing program crashes when simple functionality is added.
