When comparing Microsoft Segoe UI Mono vs Panic Sans, the Slant community recommends Panic Sans for most people. In the question“What are the best programming fonts?” Panic Sans is ranked 36th while Microsoft Segoe UI Mono is ranked 45th. The most important reason people chose Panic Sans is:
Like its parent DejaVu and grandparent Bitstream Vera, this has tall and easily read letters.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Great readability
Segoe UI Mono is a very readable font.
Pro Tall and legible
Like its parent DejaVu and grandparent Bitstream Vera, this has tall and easily read letters.
Pro Clearly distinguishes clashing characters
Panic Sans has added uniqueness for characters that are easily confused, such as "0" and "O", "l" and "1".
Pro Clarity and appealing to the eye
There is great line spacing and italics in Panic Sans.
Cons
Con The zero is not slashed
The zero is not slashed, which causes some problems when scanning source code. This is not an issue when the IDE supports coloring (like all major modern IDE's), but still there are instances where this is not the case. A primary example are T4 templates, where Microsoft has not yet provided coloring support.
Con Line spacing is small
This is a "pro" to me but some folks dislike the smaller space between lines (which is why it raises the underscore, which might otherwise vanish).