When comparing Logitech G500 vs Zowie EC2-A, the Slant community recommends Zowie EC2-A for most people. In the question“What is the best gaming mouse?” Zowie EC2-A is ranked 4th while Logitech G500 is ranked 8th. The most important reason people chose Zowie EC2-A is:
The Zowie EC2-A is made of high quality plastic that's lightly coated to help with grip. The buttons click easily and the rubber cable is thin and flexible. All of this combined gives a feeling of quality, while also being functional as a high-end mouse.
Specs
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Pros
Pro Adjustable weight
This gaming mouse also comes with weights (6 weights of 1.7g, 6 weights of 4.5g) that can be added on with a maximum of 27g of weights at a time.
Pro Thumb-rest
The Logitech G500 has more an edge on the left side for users to rest their thumbs.
Pro Braided cord
The Logitech G500 gaming mouse comes with a braided cable.
Pro Great for palm grip
Clearly designed specifically for palm grip.
Pro Onboard memory allows saving settings on the gaming mouse itself
The onboard memory will allow the user to store on custom profile no matter what PC they plug the device into.
Pro Dual-mode scroll wheel
This mouse has two scrolling modes - notched and freescrolling. The modes can be switched on-the-fly with a button located just below the scroll-wheel.
Pro The thumb buttons that are close enough together to be used in FPSs
Pro 10 programmable buttons
There are ten programmable buttons on the device.
Pro Horizontal click scroll wheel
The mouse wheel can be clicked down in the center or to the left and right. This created three different buttons in one.
Pro On-the-fly CPI switch on the side of the left click
There is a switch on the side that allows for on the fly CPI switching.

Pro Great value
Pro Well built
The Zowie EC2-A is made of high quality plastic that's lightly coated to help with grip. The buttons click easily and the rubber cable is thin and flexible. All of this combined gives a feeling of quality, while also being functional as a high-end mouse.
Pro Excellent accuracy
The Zowie EC2-A delivers accurate mouse cursor movement that is essential to any gaming mouse. The Avago 3310 sensor used by this mouse is exceptional. It delivers a true portrayal of mouse movement with no jitter, acceleration or prediction. The available DPI choices of 400/800/1600/3200 are all native and should ensure an equally good performance, regardless of which one is chosen.
Pro Gets all the little nuances that make a mouse comfortable to use just right
The left and right mouse buttons have small grooves to help fingers rest in place. The left side lets the thumb grip the mouse comfortably. The side buttons are in an easily accessible, yet unobtrusive position. The coating is slightly textured to help you control the mouse confidently.
EC2-A weighs just 94 grams, making it light enough for quick mouse movements and won't cause fatigue after extended use. At the same time, the mouse feels solidly built.
Its elegant, ergonomic design is suitable for most hand sizes regardless of the way you hold it.
It's worth noting that Zowie offers the EC1-A version for larger hands.
Pro Button switches click easily
Although the buttons have Huano switches, which are more stiff, the shell of the mouse somehow negates this and makes them click easily, just like typical Omron switches.
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Pro No extra cruft
There's no advanced functionality or accompanying software. There are just 5 buttons and the only settings you can adjust are CPI, polling rate and lift-off distance. And only in preset intervals via specific mouse button combinations. It's a mouse that focuses on the essential factors only - comfort, performance and build quality - all of which it excels at. It doesn't get distracted with anything else. If you think all the bells and whistles that come with gaming mice are unnecessary, this just might be what you're looking for.
Cons
Con Not produced anymore
Logitech G500 was replaced by G500s in 2013 and that in turn was replaced by the G502 Proteus Core in 2014.
Con Old

Con Too heavy even without weights
Con Scroll wheel is too loose
Clicking the scroll wheel is not precise and often the user will left or right click the wheel instead of actually clicking the center click.
Con Suffers from acceleration
All Avago ADNS-S9500 laser sensors suffer from acceleration issues and being that is the sensor used in the Logitech G500 it is a problem that this mouse suffers.
Con No driver for Mac
Con Limited customizability
None of the buttons can be rebound, there are no macros, profiles, or customizable weights. And while the Zowie EC2-A allows you to customize the most important performance settings - CPI, lift-off distance, and USB polling rate - their customization is limited to preset intervals.
Con DPI switch can't be accessed during use
The DPI switch is a button that can’t be accessed while in use because it's located under the mouse.
Con Extra travel on side buttons
Side buttons have a bit of pre-travel. You have to press in about 1mm more than usual for the mouse to register the side button clicks. Some may find this annoying, but it helps avoid accidentally clicking side buttons in-game.
Con DPI colors annoying and can't be customized
The scroll wheel has an LED that changes color depending on your DPI setting, but the corresponding color cannot be customized.
Con You have to learn button combinations to change settings
The Zowie EC2-A has no accompanying software. Settings have to be changed through various button combinations. As a result the initial setup can be a bit of a hassle.
