When comparing MultiBootUSB vs Easy2Boot, the Slant community recommends Easy2Boot for most people. In the question“What is the best software for creating Live USB (from ISO files)?” Easy2Boot is ranked 5th while MultiBootUSB is ranked 12th.
Ranked in these QuestionsQuestion Ranking
Pros
Pro Allows "persistance" for select ISO's
You can create a "persistance" file of up to 4GB (depending on USB stick space) for many current live CD ISO's, which means you can live boot, install a few things, save a few docs, then shutdown & move to another PC with the same files intact (tested by installing Minecraft :)).
Pro Multiplatform
Windows, Debian package, RPM & source available along with a number of unofficial builds (Arch, Slackware, ROSA, Gentoo).
Pro Includes Ventoy
Pro Direct UEFI-booting from ISOs, WIM files, Win Install ISOs, VHDs, .imgPTN files
Secure Boot works for most payloads.
Pro Supports multiple Secure Boot UEFI by 'switching-in' different image files
Pro Easy2Boot is a multiboot USB drive
Rufus and Etcher are single-boot.
Pro Can Secure UEFI64-boot and run non-secure ISOs/payloads
Pro Over 1 million downloads
Pro Highly customizable boot menus
Cons
Con Not Open Source
Author amalgamates his content with the content of others. It's not Open Source and may well have closed source and copyright restricted content.