When comparing OpenSUSE vs Nix os , the Slant community recommends OpenSUSE for most people. In the question“What is the most secure Linux distro?” OpenSUSE is ranked 15th while Nix os is ranked 16th. The most important reason people chose OpenSUSE is:
The packaging team is dependable resulting in system updates that come in a timely fashion and systems which rarely, if ever, break due to packaging. The versions of software that are selected and the configuration of them is typically extremely high quality.
Specs
Ranked in these QuestionsQuestion Ranking
Pros

Pro Extremely reliable
The packaging team is dependable resulting in system updates that come in a timely fashion and systems which rarely, if ever, break due to packaging. The versions of software that are selected and the configuration of them is typically extremely high quality.
Pro Easy installation and administration
openSUSE makes use of a GUI tool called YaST to install and setup an openSUSE system.
YaST is very easy to use and makes the process of installing and maintaining an openSUSE installation a breeze.
Pro Easily get packages from other sources
SUSE Build Service offers packages from the same sources as Fedora, Debian, Ubuntu, SUSE Linux Enterprise and other distributions. This is the most underused package tool in Linux today.
Pro Probably the best KDE desktop experience
Both Gnome and KDE desktop options are well polished to fit with the opensuse theme and environement, so either desktop is a great choice.
Pro Very stable
Stable, reliable, rock solid.
Pro Amazing choice for both newbies and power users
OpenSUSE is very easy in terms of installing packages, administration and customization, yet very powerful in the same. Every user should find his own piece of cake in this OS.
Pro Supports RPM packages
Popular format shared with distros like Fedora, RHEL, Scientific Linux, Mageia etc.
Pro Built-in drivers
Does the job needed and has the hardware drivers for the application built-in by the H/W supplier.
Pro Dedicated professional community
Directions on other desktop Linux's often force you to use GUI packages or have steps that introduce security issues.
OpenSUSE has a professional community and directions are usually geared toward GUI and CLI with similar steps.
Pro "Tumbleweed" Rolling Release
Regular and easy upgrades to stable and well tested software.
Pro Feature rich
It comes standard with a large number of pre-added applications that sort out your day-to-day use.
Pro YaST
Best administration and setup tool.
Pro One-Click install
Much better system then other distros for installing any package. It is as simple as clicking on one button and typing in your password. Adds a repo to your system keeping everything updated at the same time.
Pro Fast
Applications feel fast.
Pro Convenient package management with Zypper
Fast, reliable, powerful and almost impossible to leave a broken system.
The Yast interface will also give you access to a Zypper GUI if you are uncomfortable with the command line.
Pro Outstanding community support
OpenSUSE has a VERY active user community. Questions on forums are generally answered in minutes.

Pro Great for Haskell development
It has all of hackage in it's package manager (which is confusingly named "nix" as well) due to being based around hashing and allowing you to compile in a sort of virtual machine (really just changing the PATH variable temporarily) it solves many of the versioning problems that you commonly have with cabal. Here's a tutorial (there's many others as well) http://www.cse.chalmers.se/~bernardy/nix.html.
Also I should note that you can use the package manager a la carte on Mac and most any linux distro.
Pro Upgrading the system is extremely reliable
Since NixOS stores all its packages in isolation from each other in /nix/store
and because of the declarative configuration model, upgrading NoxOS systems is extremely reliable. Furthermore, it gives you the ability to roll back upgrades.

Pro Extremely reproducible state of installation
Every package in your system is generated from a configuration file. This makes it very easy to reproduce that environment. Just copy the config file into a new machine and it's done.
Pro Versatile snapshot system
You can use and test snapshots without rebooting. Booting into snapshots or test configurations is possible without risking the system's stability.

Pro Has docker like system built in
Pro Allows parallel configurations for multiple projects
As everything is isolated, you can have on the same machine multiple configurations to meet project requirements that would be mutually exclusive on other OSes.
Cons
Con Some clear differences from other Linux distros
This might be a systemd issue or OpenSUSE specific, but changing certain text files does not update things. They must be edited in YaST, or in /etc/sysconfig/
Con Old kernel by the Leap version
Kernel in Leap 42.3 is in version 4.4, that's pretty old.
Con Poor support for nVidia drivers in Tumbleweed
No native driver support and nouveau may be broken, especially for KDE, and not suitable for some GPUs.
Con Bloated and slow
Con Short lived distro
Every release lasts 18 months only before needing a major upgrade.
Con Updates
Not a huge problem, but Tumbleweed is better updated via the command line.
Con Massive ISO download
The base ISOs are over 4 gigs, so be prepared for a very long DL if you have slow internet. There's a network installer version, but that just delays the long DL.
Con Bad support to NTFS fotmat.
Con Limited community support
The community is fairly small, and there is no indication on the forums regarding when a issues will be solved.
Con Packman repository has to be added to have good software support
Con Startup takes a long time
Con Updates
Not a huge problem, but Tubleweed is better updated via the command line.
Con Complex permissions policy

Con The configuration language is hard to figure out
For good reason. It's a purely functional language. However not even close to bash.
