When comparing Tails vs Pop!_OS, the Slant community recommends Tails for most people. In the question“What are the best Linux distributions for desktops?” Tails is ranked 15th while Pop!_OS is ranked 47th.
Ranked in these QuestionsQuestion Ranking
Pro Privacy focused
Pro Has TOR built-in
Use the Internet anonymously and circumvent censorship; all connections to the Internet are forced to go through the Tor network.
Pro A separate NVIDIA version
Most linux distros seem to hate Nvidia's graphics cards e.g. Fedora and OpenSUSE. System76 have decided to be kind. They have decided to form a good relationship with Nvidia fans and Nvidia itself. By creating a separate installation media that is dedicated for providing support to Nvidia's graphics cards. Even going as far as putting Nvidia's driver updates on Pop!_Shop for users to easily access and install.
Pro Made by a hardware seller
System76 is a hardware company. It configures machines to ship with Linux pre-installed. This means its entire business model centers around delivering a quality desktop Linux experience.
As a result, the company pours more attention onto the desktop. It can fix visual issues and may be able to provide a smoother overall experience than you would have installing a different version of Linux on your machine yourself. Providing Pop!_OS also empowers System76 to make certain fixes for users directly rather than having to coordinate with Canonical or the broader Ubuntu community.
Pro Pop! makes GNOME look really good
If you're a fan of flat desktop interfaces reminiscent of Material design on Android, you'll like the theme that comes as a default in Pop! OS. The desktop and title bars all use a bright turquoise theme that makes the interface feel happy and borderline retro-chic. I found it to be like something you'd find printed on a ringer t-shirt.
Pro Nice gnome theme dy default
Has nice gnome theme looks really good
Con Not for daily use
Tails is a privacy focused Linux distro. The updates that you will receive are only for improving privacy and not for improving user experience.
Con Saved states are not present for security
For security reasons, saved states are not supported in Tails. Files can be stored in a separate, persistent volume which must be accessed with a root password. Personal settings (e.g. -- keyboard layout, window settings, etc.) are not saved persistently across reboots. This can be a hindrance for anyone not using English as their language, or not using a QWERTY keyboard layout.
Con You can't install it to a hard drive
Con Slow internet
Tails uses the TOR network and as a result the internet on your computer will be very slow.
Con 64-bit only
Some older PCs still have 32 Bit processors. This limitation will be a major con for those who use an older PC since they will not be able to install, run it in a VM or live media