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When comparing NixOS vs Artix Linux, the Slant community recommends Artix Linux for most people. In the question“What are the best Linux distributions for desktops?” Artix Linux is ranked 7th while NixOS is ranked 19th.
Specs
Question Ranking
Pros
Pro State of the art package manager
Atomic non-destructive upgrades / rollback of a system upgrade / declarative reproducible system configuration / unprivileged installation of packages / transparent source or binary deployment.
Pro Minimal
You can start with a minimal environment and add packages and software to suit your needs as you go along.
Pro Reproducible system
NixOS is configured using the Nix package manager, allowing your system to be replicated and kept in sync across multiple machines. Great for keeping a laptop and desktop in sync.
Pro Robust
Packages don't break after a NixOS upgrade as they are prone to with other distros (especially Arch).
Pro No systemd
Pro Runit
Artix actively supports the runit init system known from Void Linux. (Equally besides the OpenRC init system known from Gentoo).
Pro Close to bare Arch Linux
No learning curve if you're coming from Arch or any of its derivatives.
Pro Lightweight
Only the software you would need like Terminal emulator, file manager, media player and a browser.
Pro Compatible with Arch Repositories
It is fully compatible with almost all packages from community, extra, multilib and AUR.
Pro Rolling distro
Pro Flexibility
You can have a functional system in less than 10 mins using GUI installer OR you can do it "the Arch way".
Cons
Con Documentation is not good
A lot of the documentation of various functions is buried on the source code, their respective manuals, or non-existent. The documentation, the conventions, and the scattered toolchain really made searching for stuff easily missable.
Con A configuration change might end up bricking your system
Con No systemd
Some packages flat out won't work because systemd is non existent, sadly pipewire needs systemd to run. Hopefully Pipewire becomes usable soon. Edit: Pipewire does work but you will have to make a startup script.
Con Few Arch packages might not be available yet
Developers are working migrating all packages into their own repositories while ensuring there's no systemd malware.
Con No tiling WM (i3/sway) out of the box
