When comparing NixOS vs MX-Linux, the Slant community recommends MX-Linux for most people. In the question“What are the best Linux distributions for desktops?” MX-Linux is ranked 9th while NixOS is ranked 28th.
Ranked in these QuestionsQuestion Ranking
Pro State of the art package manager
Atomic non-destructive upgrades / rollback of a system upgrade / declarative reproducible system configuration / unprivileged installation of packages / transparent source or binary deployment.
Packages don't break after a NixOS upgrade as they are prone to with other distros (especially Arch).
Pro Reproducible System
NixOS is configured using the Nix package manager, allowing your system to be replicated and kept in sync across multiple machines. Great for keeping a laptop and desktop in sync.
You can start with a minimal environment and add packages and software to suit your needs as you go along.
Pro Supports non-free drivers
Pro MX Snapshot: lets you make your own distro
Can create your own ISO (snapshot) and use it either as live-session and install back when needed.
With the (pre-installed) Snapshot tool you can easily create an ISO of your running system and then save it to a USB (or other media) and use "your own" distro as a live session or install back whenever you like (even on a different PC with different specs with no issues). You can even give that customized ISO to friends (selecting "non-personal" ISO when creating the snapshot; thus resetting the accounts & passwords and Home folder etc.).
Also you can save that ISO directly encrypted via MX Live USB Maker tool. Again, you can install MX encrypted during installation with just ticking a box, no matter if it's the official ISO or your snapshot.
Pro Easy to use
Pro Easy install
Pro No systemd
Pro Very stable
Pro Based on Debian
It is based on Debian and not based on Ubuntu.
Pro Good MX Tools and Package Installer
MX Linux comes with its own set of tools called MX Tools, designed to make life easier for users.
Pro Live-Session boots fastest after Puppy
After Puppy Linux (which's aimed to run from RAM and which is smaller in size) the second fastest (head & shoulders) booting one (together with the sister project antiX) and also has the option "toram" to run from RAM. Yes, not only when compared to full distros, even far faster than small sized or tiny distros, especially when booted to "live-session", about 2 - 2.5 times faster on an old single core laptop.
Pro Can also be used as an emergency tool
It has almost all tools to repair non booting systems or recover files & folders and save them on a safe place. And when thought together with it starts quick on live-session. In addition, you can do these with "your own", customized distro (snapshot).
Con Documentation is not good
Con A configuration change might end up bricking your system
Con Uses a text-based installer
Con Remixed Debian testing
It's mainly a Debian stable with some recompiled/backported Debian testing packages.
Con Causes overheating on some hardwares
Other debian based XFCE distros- Xubuntu, Debian XFCE, Devuan leave small footprint on system whereas MXLinux uses too much CPU resources on same system.
Con 10s of media players preinstalled
Con Old software
Many software applications are older.
Con Longer boot time
Con Too much customization
Con Only one Desktop Environment
Con More than 50 tweaking softwares pre-installed
Con Includes non-free drivers
Con Installer and configuration tools are different
Installer and configuration tools are different and can take some time getting used to.