When comparing Microsoft Expression Design vs MyPaint, the Slant community recommends MyPaint for most people. In the question“What are the best drawing programs?” MyPaint is ranked 7th while Microsoft Expression Design is ranked 13th. The most important reason people chose MyPaint is:
MyPaint mostly consists of the canvas. The interface to select different brushes can be brought up if needed, but it generally stays out of the way of getting things done.
Specs
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Pros
Pro XAML support
One of the few drawing programs that supports the XAML vector format, used by .NET WPF applications.
Pro Interface gets out of the way
MyPaint mostly consists of the canvas. The interface to select different brushes can be brought up if needed, but it generally stays out of the way of getting things done.
Pro Good support for pressure sensitive graphics tablets
MyPaint was designed specifically with pressure sensitive graphics tablets in mind.
Pro Good media emulation
Pro Forgo the need to resize the canvas
If a user needs a bigger canvas all they need to do is zoom out instead of re-sizing.
Cons
Con Discontinued
Not supported by Microsoft anymore.
Con Windows only
Con Is not stable at all
I could not even open a png file to start without the software to freeze.
Con Not a lot in terms of image manipulation
MyPaint focuses only on drawing. It has very little in terms of post processing or image manipulation features.