When comparing 1Password vs Password Safe, the Slant community recommends 1Password for most people. In the question“What is the best cross-platform password manager?” 1Password is ranked 3rd while Password Safe is ranked 13th. The most important reason people chose 1Password is:
An iteration on the UI brings a polished look that was already good-looking to begin with. It even tries pulling in relevant app and web icons, adds credit cards logos and has little animation to make the experience more pleasant.
Specs
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Pros
Pro A clean, good-looking and intuitive UI
An iteration on the UI brings a polished look that was already good-looking to begin with. It even tries pulling in relevant app and web icons, adds credit cards logos and has little animation to make the experience more pleasant.
Pro Browser integration
Easily fill in passwords with a single keystroke combination.
Quickly add new and update existing passwords right from the browser when the login is detected by the free browser extension.
Pro Available as a standalone application, a menubar app, and as browser extensions
Offers choice.
Pro Can also store software and license keys
Pro Cloud & Wi-Fi sync
1Password offers syncing through cloud storage services such as Dropbox and iCloud and a possibility to sync locally over Wi-Fi if you opt not to use cloud storage.
Pro Easy to use autofill and password generator
Automatically logs into websites, enters credit card information, fills registration forms, and easily generates strong passwords. Password generator can be adjust to use or exclude certain characters and patterns.
Pro Can perform an audit on passwords
1Password can checks for weak, duplicate and old passwords you have stored.
Pro TouchID support
All TouchID capable devices are supported.
Pro Doesn't depend on the cloud
Unlike many other password management tools, by default the 1Password encrypted database is not stored in the cloud, but strictly locally, for added security.
Pro AES-256 encryption
Pro Warns of website vulnerabilities
A feature called Watchtower cross-references known website vulnerabilities with stored login information using a database that is updated daily.
Pro Collaborative password management
1Password offers an option to create a shared vault for sharing passwords among friends, family and co-workers.
Pro Time based one time passwords
Pro Version now supports time based one time passwords (instead of installing google authenticator)
Pro Endorsed by many high credibility security experts
This app is endorsed by many high credibility security experts (for example, Troy Hunt ).
Pro Great customer support
Pro Active community of users and active / blogging development team.
There is an immense sense of community and openness with 1Password.
Pro Periodically assessed by external security auditors and their findings are repaired quickly
Pro Makes use of keys so that password to login is never in transit
Pro Portable
Password Safe has a portable versiona, PasswordSafe2Go.
There is also PasswordSafe for U3 (still supported, but no longer available).
Pro Completely offline
This does not save or synch with any server; no connection to any external server. There is no central server to hack, no network connection to sniff.
Pro Great user interface on Mac and iOS
Since the passwordSafe is essentially an open standard multiple people can use to develop apps. The http://pwsafe.info/ apps for Mac and iOS are really excellent (paid) management options.
Pro Anyone can verify the code since the software is open source
Anyone can review the code.
Cons
Con Lacks native Linux support
No native app is available specifically for Linux making this a poor option for Linux users. Though there is 1Password for Families which offers a web app that can be accessed in any browser, but it does cost at least $5 a month, so not free.

Con Not free/libre
This application is proprietary, and thus cannot be modified, freely distributed, or trusted to be secure.
Con Lack of Google Drive sync
Only icloud, wifi and Dropbox support.
Con No longer available as a standalone app
It's now a subscription based app
Con Does not auto-fill and generate passwords in Microsoft Edge for Windows 10
The 1Password Edge extension doesn't work as well as in other browsers, as it can't auto-fill and generate passwords. Only LastPass seems to have a fully-functional browser plugin for the Edge browser at this time.
Con Tough/impossible to get on Chromebook
Con Lacks native BlackBerry and Windows Phone applications
No native app is available specifically for BlackBerry or Windows Phone devices.
There is a feature called 1PasswordAnywhere that's built-in to the 1Password vault, which provides read-only access of the database. However, you can use the web app from your phone. Though this may not be optimal for everyone, especially when considering the service is paid.
Con Unreasonably high price
It has a high monthly subscription price
Con Backups needed
You have to be diligent with your backups. You have to be careful when synching copies across your devices.
Con No official browser integration
No browser plugins available.