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When comparing Adélie Linux vs Guix, the Slant community recommends Guix for most people. In the question“What are the best Linux distros that don't use systemd?” Guix is ranked 16th while Adélie Linux is ranked 41st. The most important reason people chose Guix is:
For those with a clear focused concept of what is wanted, after building, the build can be replicated in a blink on countless machines. Both GUIX and shephard are complex but also a breath of fresh air.
Specs
Question Ranking
Pros
Pro Simple packaging system
Built on Alpine's APKBUILD system, which is an accessible and simple packaging system. If you're familiar with Arch's ABS or Gentoo's ebuilds, APKBUILDs are a breeze.
Pro Is pure Python 3
There is a hard and fast rule against Python 2 software in the main repositories, with efforts focused on adapting software to use Python 3 where possible.
Pro Small and performant
A standard installation takes under 200 MB. Only the bare necessities are included.
Pro Inviting and receptive development team
The people building the distro are knowledgeable and helpful when issues arise. Merge requests are actively suggested and reviewed, and the developers thank users for taking the time to learn the distro.
Pro Atomic package management without bloated init/supervision systems
For those with a clear focused concept of what is wanted, after building, the build can be replicated in a blink on countless machines. Both GUIX and shephard are complex but also a breath of fresh air.
Pro Secure rootless installation
While the whole system can be configured using a declarative file with sufficient privileges. Users can install any package in their own local profile with a single command without root.
Pro A truly advanced operating system
Solves modern problems of software management in one concise, coherent, and fully integrated system.
Cons
Con Not (yet) ready for Linux newbies
As of November 2018, there isn't an installer yet. If you're familiar with installing Arch or Gentoo (via chroot, fdisk, et al) then it's no big deal. An installer framework (called Horizon) is in the works.
Con Is pure Python 3
Python 2 support is not supported by the distro, so many older upstreams who haven't adapted to Python 3 yet will need their software patched to work (this is both a pro and a con).
Con Somewhat limited package set for servers
As of November 2018, it's still missing some server software. It's primarily a desktop-oriented distribution, but accepts server packages and progress has already been made on that front, including lighttpd, apache, and php-fpm. Contributors are already bringing more server software to the distro, including certbot, cgit, and Nextcloud.
Con Not for newbies, neither for seasoned professionals, unless raging against conformity with artful purpose
