When comparing Murus Pro vs One Periodic' s Hands Off, the Slant community recommends Murus Pro for most people. In the question“What is the best OS X firewall?” Murus Pro is ranked 3rd while One Periodic' s Hands Off is ranked 4th.
Ranked in these QuestionsQuestion Ranking
Pros
Pro Free version available
Pro Configures macOS native PF firewall
Configures already existing network level firewall - which means very little overhead (app doesn't even need to run in the background)
Pro It lets you control application's disk writing permissions as well
Besides giving you control over what applications in your computer can access the internet, it also lets you select which ones are allowed to write to your disk, so if you're very paranoid about data leaking, this app is for you.
Pro Prevents applications from phoning home
It can block both incoming and outgoing connections.
Pro User friendly interface
It resolves DNS queries, so instead of popping up with a generic question like "I wan to to connect to 17.173.255.222 on UDP port 16384", a more informative popup will tell you "I want to connect to talk.google.com".
Cons
Con Reading required for an average user
If you haven't had a course in computer networks there is some required reading for you to understand the configuration
Con Expensive
It's expensive when compared to other firewall software out there.