When comparing Mithril vs zUIx.js, the Slant community recommends Mithril for most people. In the question“What are the best React.js alternatives?” Mithril is ranked 8th while zUIx.js is ranked 23rd. The most important reason people chose Mithril is:
Most other frameworks either offer a huge API to deal with model and view synchronization, or defer to other libraries & plugins to cater for relatively simple use cases. Mithril's API is tiny but complete. The natural reaction is to assume something is missing, but as you build you realise you incredibly fast, powerful and rich applications can be built using nothing but Mithril.
Specs
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Pros

Pro Small, easy to learn API
Most other frameworks either offer a huge API to deal with model and view synchronization, or defer to other libraries & plugins to cater for relatively simple use cases. Mithril's API is tiny but complete. The natural reaction is to assume something is missing, but as you build you realise you incredibly fast, powerful and rich applications can be built using nothing but Mithril.

Pro Fast rendering
Mithril's loading times are very fast. This is because it's templates are compiled first and then served to the browser and because it uses a virtual DOM. The virtual DOM is a virtual tree containing all the nodes of the real DOM, every time anything changes in the virtual DOM, Mithril does not re-render the entire (real) DOM, instead it just searches and applies the differences.

Pro No need to learn another syntax to write views
Most MVC frameworks use HTML templates to render their views. They are good and useful because they are easy to read and understand. But they add more complication to an app because it's practically a new language and syntax that needs to be learned.
Mithril argues that separating markup from logic is just a separation of technologies and not concerns, so you can write Mithril views in JavaScript. Writing them in JavaScript also makes it easier to debug them (HTML templates can't be debugged).

Pro Familiar to people used to MVC
Doesn't lock you into any complicated conventions or structures, only one function is required to create either a Controller or a View. You're free to implement your architecture exactly as you want, so you can focus on the purpose of MVC, making connections between computer data and stuff in the end user's head.

Pro Small size
Weights just 8Kb gzipped and has no dependencies. A reactive stream module can be added for one extra Kb.
Pro Great documentation
Mithril has a large and expansive documentation despite it's relatively small API. Mithril's GitHub repo has more documentation than actual source code. None of that documentation is auto-generated
Pro Allows a smooth transition from other UI frameworks
One thing you need to start using Mithril is just a DOM node. With Mithril a developer is able to introduce the library step by step.
Pro Allows you to choose which JavaScript libraries to integrate in your project
Mithril gives to the developer the flexibility to chose the best JavaScript library to use for a specific task.
A huge framework like Angular instead forces you to use their API, which does not necessarily evolve as fast as the JavaScript ecosystem. Therefore you may end up in case when you are stuck using an API which is just not the best in terms of performance
Pro Can be used without build systems
It's plain old JavaScript, can be used without webpack, gulp or grunt, just include it into your HTML and start writing your app.
Pro Does not force you into a predefined structure
Mithril's API is pretty small compared to other frameworks. It forces developers to solve problems in JavaScript rather than in Mithril. Other frameworks with massive APIs force you to think in a way that suits the framework. Mithril doesn't do that.
Pro Ease of use
Requires only basic HTML/Javascript knowledge.
Pro In-browser bundler
Can pack assets and resources in the browser console with no need for any external tool.
Pro Component-based
Creating a component is just a matter of creating 3 small files (html, css, js).
Can share and load components across websites.
Pro Web Starter Project
If you like Node.js and automatic build system, the zuix-web-starter is a "blank" web project featuring LESS, Markdown, Minify, Eslint checks, automatic bundling, PWA optimizations and much more.
Pro Lazy-loading
Built-in lazy loading feature. Almost transparent.
Pro Templates
With automatic fields mapping (data binding).
Pro jQuery alike helper
Built-in DOM helper. Basically a lite subset of jQuery.
Pro Examples
The zKit site is a collection of example components ready to use as-is or as a base for creating your own components.
Cons
Con Small API can make it unsuitable for larger more complex projects
Mithril's small API and small number of functions while helpful for small projects and applications where speed is needed, can add another layer of complexity in larger more complex applications where a more extensive API is needed out of the box.
