When comparing ErgoDox EZ vs Kinesis Advantage2, the Slant community recommends ErgoDox EZ for most people. In the question“What are the best keyboards for programming?” ErgoDox EZ is ranked 3rd while Kinesis Advantage2 is ranked 8th. The most important reason people chose ErgoDox EZ is:
You can map any key to any position easily using a simple GUI, including making hardware key layers. And, since the firmware is open source, you can modify it to do anything you want. Many of the hardware components can also be altered/replaced by equivalent parts.
Specs
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Pros
Pro Ultimate customizability
You can map any key to any position easily using a simple GUI, including making hardware key layers. And, since the firmware is open source, you can modify it to do anything you want. Many of the hardware components can also be altered/replaced by equivalent parts.
Pro Split design lets you optimize positioning
You can arrange each side of the keyboard to match your hand positions. Helps keep your body straight and improve your posture.
Pro Comfortable for those with broad shoulders and large hands
Because of its split design, the ErgoDox lets you optimize the positioning of its halves according to what's best for your body shape, even if you have broad shoulders and large hands.
Pro Open source
The ErgoDox has an open design, so if you want to modify anything at all, you can fork the Github repository.
Pro Many easily accessible keys for touch typists
There are more keys which are easily accessible for touch typists than on common keyboards.
Pro More actions for the thumb
Unlike other keyboards, like the Lexmark M15 and Cherry G80-5000, where the only action performable by the thumbs is punching the spacebar, ErgoDox has extra keys placed near the spacebar, within thumb reach. This prevents the thumbs from being a bit redundant.

Pro Key rows are aligned
Almost all the keyboards have a small row offset (for example, on a standard QWERTY keyboard, the A key is not directly below the Q key. On the ErgoDox, this isn't the case: keys form straight columns. Together with the movability of the two parts you can stretch your fingers straight on, not slightly sidewards. This helps with touch typing, since you just need to stretch your fingers straight onward to reach the key above, rather than stretching it onwards and sideways.
Pro Firmware updates
Because of the nature of ErgoDox, within an open source community, there are advancements in firmware being made continuously.

Pro Customization settings saved on the keyboard
With most programmable keyboards, you have to use their software in order to save and reuse your customizations. Using such keyboards on other systems "degrades" them to their default setting. Since with the ErgoDox the settings are saved directly on the keyboard, no matter the system where you're using it, your macros, tap dances and layers are always available.

Pro Split design forces correct hand position
The Ergodox doesn't allow you to reach over the centerline to hit T and H with a single finger, or whatever other bad habits you might have. The split design forces you to keep your hands in the right position.
Pro ErgoDox EZ offers a 2-year warranty
The pre-assembled version offers an extensive 2-year warranty, provided you haven't taken it apart or physically broken it.
Pro Small to carry
You can put the keyboards together, making it very easy to carry around.
Pro Clusters of keys under each thumb means less reaching
Having multiple keys under the thumbs lets you keep the rest of your hands still, and helps prevent reaching. For example, the backspace key on a regular keyboard is way in the top right corner, while on the Kinesis keyboard it's under the left thumb. So, to hit the backspace button you just need to move your thumb while on regular keyboards you need to move your whole right hand and stretch your pinky to reach it.
Pro Optimised, ergonomic shape that significantly reduces the risk of RSI
This keyboard is sculpted to fit the curvature of your hand more naturally than regular flat boards. This helps reduce the risks of suffering repetitive strain injuries.
Pro No need to constantly move hands sideways
One of this keyboard's best features is that the keys are vertically aligned in straight columns, so that you're not constantly exercising the muscles to move your fingers slightly to the left or to the right. It makes a huge difference.
Pro Comfortable palm rests
The large, raised palm rests provide comfort while typing.
Pro Prepared for macOS, Windows and Linux
Besides the option of easily changing between pre-programmed layouts of these 3 systems, extra OS-specific keycaps come with the keyboard.
Pro Very programmable
This keyboard has several programmable options, like Macro recording, key remapping or keyboard layout (the keyboard can be changed from QWERTY to Dvorak with the touch of a button).
Pro No undesirable movements
Because of its size, this keyboard stands firmly on the desk and doesn't suffer from unwanted movement during use.
Pro Dvorak built in
The keyboard has the dvorak layout built in, so you can switch with a keypress.
Pro Tweaked layout that saves your hands
This keyboard has numerous ergonomic advantages over a keyboard with a standard layout. Some of them are obvious and some are subtle, but they are synergistic and result in a typing experience that places far less stress on the hands. Learning a tweaked keyboard layout is a small price to pay to avoid RSI (repetitive strain injury).
Pro No thumb conflict over the spacebar
On common keyboards, both thumbs rest over the spacebar, meaning they can knock against each other. On the Advantage 2 keyboard, only one thumb can press the keyboard, eliminating this problem.
Pro Good for learning how to touch type
This layout, because of its uniqueness, is perfect to learn touch typing. Even for those that were never able to learn it with common keyboards. It still requires practice to get proficient, of course.
Cons
Con Expensive
Getting a complete kit from Massdrop costs about $400. Sourcing each part individually ends up a bit under $200.
You can get a preassembled keyboard from ergodox-ez.com from 270$ with 2 year warranty
Con Firmware has some hiccups sometimes
Usually this doesn't get in your way, but sometimes it does.
The repository is actively developed, so errors should be resolved within no time, or at least you get decent help.
Con Needs to be assembled
This can be fun, but some people just want a working keyboard without having to spend three hours with a soldering iron. It's tricky to find pre-assembled ErgoDoxes, and they're not mass-produced. It is also possible to commission an enthusiast to build one up as well. Some Massdrops of the ErgoDox kit did came with an option allowing one to choose whether to have it pre-made or not.
However, you can order and ErgoDox EZ preassembled here.
Con Tends to move around during use
Due to its split structure and lack of sturdiness, it tends to move during use.

Con Difficult to source individual components
You have to either source the individual components and build it yourself or wait for a Massdrop group purchase.
However, you can order it preassembled here.
Con Hard to use with small hands
Because of its size, it's hard to use for those who have small hands.
Con Can be a bit flakey at times
The downside of this keyboard is that it can occasionally act up. The biggest problem is that the up-event for a key occasionally gets lost and then some key will auto-repeat until you press it again. Or even worse, it's a key that has no visible effect like an Alt key, and then you have to figure out which key it is that is in the virtual down position, and press it again. It has had this same problem for the last 20 years. You learn to live with it for the sake of your hands.
Con Not great for gaming
This keyboard is amazing for typing, but not great for gaming. Many games make intensive keys such as the Arrow keys or the Alt, Control and Shift keys. With this keyboard, it's not very comfortable to use them so frequently.
Con Proficiency means overcoming a learning curve
Becoming an expert at using this keyboard’s optimized design needs time and patience, since it’s so different from what most people are used to. Some of its drastic layout changes can be disorienting at first. For example, the four arrow keys are separated: up and down on the right side cluster; left and right on the left side cluster.
It’s also built to enforce healthier hand posture and movements, that may feel weird at first. For instance, the keyboard trains you (using a deactivatable key feedback) to press keys smoothly instead of smashing down, which reduces hand strain. Usually, it takes between two to four weeks of regular use to feel completely comfortable at using this keyboard.
Con Not for heavy shortcut users
Con Different switches for the function keys
The functions keys are not build with the same switches than the other keys: they use Cherry ML switches instead of Cherry MX Brown switches. Because of their shorter travel distance, the ML feels quite different. It's awkward to have such different sensations for different parts of the keyboard.
Con Quite bulky, therefore not very portable
As a direct consequence of its unconventional ergonomic shape, the Advantage2 is quite bulky. At 16.5 in’ x 8 in’ x 2.88 in’ (419 mm x 203 mm x 73 mm), it's not the most portable keyboard.
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