When comparing Affinity Photo vs Inkscape, the Slant community recommends Affinity Photo for most people. In the question“What are the best graphic design programs?” Affinity Photo is ranked 1st while Inkscape is ranked 2nd. The most important reason people chose Affinity Photo is:
Pay once, get updates forever.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Lifetime updates
Pay once, get updates forever.
Pro Interface will be familiar to those coming from Photoshop
The interface, especially the Photo persona, is laid out in way that's very similar to Photoshop - a panel for icons for tools on the left, a panel for information and settings on the right.
Pro Compatible with Photoshop PSD files
Affinity Photo can import and export .psd files.
Pro Great performance
Uses the GPU extensively for fast speed on any platform.
Pro Supports layer styles
Layer styles allow non-destructively applying effects to a layer.
Pro Personas allow separation of concerns
At a high level the interface is organized into broad groups of tools called Personas. Personas like Photo for in-depth image manipulation, Liquify for warping the image, Develop for basic RAW photo development and Export for exporting. Each persona displays only those tools that are needed for that task.
Pro Powerful effects
Dozens of visual effects available. All run extremely fast with live previews
Pro Non-destructive adjustment layers
Extensive adjustment layers are non-destructive.
Pro Everything is well organized
Easy to find and use tools.
Pro Runs faster than Photoshop's old code
Pro Lots and lots of undo
Pro The easiest, even easier than photoshop
Pro The perfect combination of Photoshop and Lightroom - all in one
Pro Supports Photoshop brushes, shapes, etc.
Pro Many tutorials
But still it does not actually matter which tutorial you're actually watching, Photoshop or Affinity's, they are pretty much the same.
Pro Very, very cheap for such an app
Pro Has an iPad app
Pro Decent functionality, 100% comparable with Photoshop
Pro Much more lightweight than photoshop
Pro RAW file editing
Pro HDR image editing
Pro Powerful, cheap and lightweight
Pro Very modern and intuitive interface
Pro Color correction
Pro Very fast to learn
Takes about 20 mins, it's that easy.
Pro Growing decently fast
Pro Panorama creation
Pro Imports free images from Unsplash

Pro Free and open source
Inkscape is GPL-licensed and maintains public repositories.

Pro Opens lots of file types
Inkscape supports many common formats for import (including SVG, Photoshop and Illustrator) and its plugin architecture allows more to be added.
Pro Export to different file types
Files can be exported and saved as a "normal" svg, png, jpg, bmp etc. file.

Pro Cross-platform
Pre-built binaries are available for Windows, Mac and Linux. Inkscape can be built from source on additional platforms.
Pro Integrates well into a X11-System
Its uses the X11 icon theme and desktop theme(GTK).
Pro It can do anything
A very powerful software that can do pretty match anything!
Pro Measurement Tool
This tool is extremely handy and can not be found in any other vector graphics programs out there.
Pro Live Path Effects
Extremely powerful menu that offers more than 30 powerful Live Path Effects to apply to paths vastly enhancing the application functionality.
Pro Guides, Grids, and Canvas Rotation
Extremely handy features when building complex graphics using Inkscape.
Pro Dark Theme Support
The new 1.0 beta 2 version finally got support for dark theme which normally is only available for commercial software like Affinity Serif, Adobe Illustrator.
Pro The new version 1.1 is looks and feels fantastic
Inskape got UI update: new dockable dialogs.
Pro Interface is available in 29 languages
Basque, British English, Brazilian, Portuguese, Catalan, Croatian, Czech, Dutch, Finnish, French, German, Greek, Hindi, Hungarian, Icelandic, Indonesian, Italian, Korean, Latvian, Norwegian (Bokmål), Polish, Romanian, Russian, Slovak, Spanish, Swedish, Turkish, Ukrainian, Urdu, Swedish.
Pro It's really easy and fun
Vector graphics can be created and edited with Inkscape.
Cons
Con Limited selection of plugins
Plugin support was only recently added to AP and not many plugins have been created for the program so far.
Con Can not import gimp or krita files
Free alternatives like GIMP (and Krita) are sort of "go to" apps you can always install and use for simple image editing or graphics on any computer. Affinity's support for Photoshop is great, but having support also for opening and editing GIMP and Krita files would make the versatility and use of this program absolutely superb.

Con Very slow startup on some systems
Depending on factors like how many fonts you have installed, Inkscape can take upwards of 30 seconds to launch.
Con Uses its own SVG-format by default
Inkscape might use SVG as its default format, however this SVG's contains some additional SodiPodi/Inkscape additions that can be troublesome if you want to import the SVG into some other application.
Con Buggy
Application is often buggy so it happens from time to time that the popup / right-click menu won't close and stays open. It crashes also sometimes randomly. This makes it almost unusable for productive / business use.
Con Crashes very often
Inkscape encountered an internal error and will close now - is one of its standard messages.
Con 1.0 is sluggish
Inkscape 1.0 uses GTK 3 which is sluggish and slow for low spec systems( eg. ARM, Celeron, Pentium, Core-i3, Ryzen 3 or Athlon ) compared to previous versions.
Con Limited work with ICC CMYK color scheme
Support for ICC color profiles only in SVG files.
Con Y-axis inverted
0,0 coordinates begin in lower left corner, not upper left corner as SVG standards define in Inkscape 0.92.x.
It seems this is now fixed in the 1.0 beta 2 version of the program.
Con A toy for facebook-ist enthusiasts, not for professionals
It's a Linux niche mumbo-jumbo, same as GIMP for raster edit .
Con Based on the GTK widget toolkit
Software is based on GTK, so it might not integrate well in non-GTK environments. It also requires many dependencies on those non-GTK desktops. It also adds dependencies to GTK-environments since it is written in C++ which requires the gtkmm wrapper/interface.
Con Mac version does not look as polished as its versions for Windows/Linux version for the 0.92.x version
It seems that Inkscape 1.0 beta 2 for Mac got some needed attention and it looks a lot better with dark theme support. native DMG installer and they got rid of X11 which is great.
Con Incompatible with previous versions
Sometimes backward compatibility breaks. For example, pre 0.92 SVGs are incompatible with later releases (due different default resolutions).
Con Since 0.91 the gradient editor is gone
It is now only possible to edit a gradient on screen. but you can't set a stop to a specific percentage anymore.
Con No support for large printing machine system
No support for large printing machine environment, except exporting the resulting artwork to PDF.
Con Under GNU GPL
It is released under GNU GPL which one of the restricted open source license.
