When comparing Affinity Photo vs Blender, the Slant community recommends Affinity Photo for most people. In the question“What are the best graphic design programs?” Affinity Photo is ranked 1st while Blender is ranked 7th. The most important reason people chose Affinity Photo is:
Pay once, get updates forever.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Lifetime updates
Pay once, get updates forever.
Pro Interface will be familiar to those coming from Photoshop
The interface, especially the Photo persona, is laid out in way that's very similar to Photoshop - a panel for icons for tools on the left, a panel for information and settings on the right.
Pro Compatible with Photoshop PSD files
Affinity Photo can import and export .psd files.
Pro Great performance
Uses the GPU extensively for fast speed on any platform.
Pro Supports layer styles
Layer styles allow non-destructively applying effects to a layer.
Pro Personas allow separation of concerns
At a high level the interface is organized into broad groups of tools called Personas. Personas like Photo for in-depth image manipulation, Liquify for warping the image, Develop for basic RAW photo development and Export for exporting. Each persona displays only those tools that are needed for that task.
Pro Powerful effects
Dozens of visual effects available. All run extremely fast with live previews
Pro Non-destructive adjustment layers
Extensive adjustment layers are non-destructive.
Pro Everything is well organized
Easy to find and use tools.
Pro Runs faster than Photoshop's old code
Pro Lots and lots of undo
Pro The easiest, even easier than photoshop
Pro The perfect combination of Photoshop and Lightroom - all in one
Pro Supports Photoshop brushes, shapes, etc.
Pro Many tutorials
But still it does not actually matter which tutorial you're actually watching, Photoshop or Affinity's, they are pretty much the same.
Pro Very, very cheap for such an app
Pro Has an iPad app
Pro Decent functionality, 100% comparable with Photoshop
Pro Much more lightweight than photoshop
Pro RAW file editing
Pro HDR image editing
Pro Powerful, cheap and lightweight
Pro Very modern and intuitive interface
Pro Color correction
Pro Very fast to learn
Takes about 20 mins, it's that easy.
Pro Growing decently fast
Pro Panorama creation
Pro Imports free images from Unsplash


Pro Free and open source
Blender is licensed under the GPL. Some Blender modules such as the Cycles rendering engine are licensed under the Apache 2.0 license.

Pro Wide import and export format support
Support lots of modern 3D formats including DAE and FBX - ideal for game developers.
Pro Has a powerful rendering engine
Blender runs the Cycles path tracing engine under the hood. Cycles is a very powerful rendering engine capable of full path tracing (light fall off, caustics, volumetrics). It is mostly compatible with OpenCL and CUDA rendering, and is implementing mycropolygon displacement features. The upcoming release has a viewport engine called EEVEE whereby you can see and interact with your work in render mode in real time!

Pro Python extensibility
Blender embeds Python 3, which can be used to write add-ons, tools, extend the interface, rig characters and automate tasks.

Pro Powerful animation suite
Blender provides a full rigging system, and automates animation by interpolating between keyframe positions.
Pro Supports both low-poly and hi-poly modeling

Pro Regular release schedule
Releases are made every ~3 months.
Pro Sculpting and 3D painting features
Although Blender's 3d painting and sculpting tools (mostly painting) are not at par with specialized software like Substance Painter, ZBrush, or Mari, it is more than capable of getting most jobs done if the user takes the time to learn and understand it.

Pro Includes video editing & compositing tools
Blender's node-based compositor has comprehensive video sequencing and post-processing features.
Pro Node based modeling support
Pro Keyboard shortcuts
Good keyboard shortcuts for everything. Keep your left hand on the keyboard and your right hand on the mouse.
Pro Very useful for a freelancer
It offers a round solution (it covers many areas and professional fields) for a freelancer, for free, constantly updated, very polished, and allowing high quality results that clients do require. After some learning, it becomes very useful for professional work.
Pro Has a large community
There's a huge community to help you get started immediately.
Pro Coherent and streamlined workflow / internal use logic
The trick with Blender is to get used to its usage philosophy, as it keeps consistent through all the application. Once you get it, every feature or addition is learnt naturally, almost effortlessly.
Pro Very versatile
You don't have to switch between software when you want to do different things. Because modeling, sculpting, composting, video editing etc can all be done in blender.
Pro Generative geometry using nodes
Cons
Con Limited selection of plugins
Plugin support was only recently added to AP and not many plugins have been created for the program so far.
Con Can not import gimp or krita files
Free alternatives like GIMP (and Krita) are sort of "go to" apps you can always install and use for simple image editing or graphics on any computer. Affinity's support for Photoshop is great, but having support also for opening and editing GIMP and Krita files would make the versatility and use of this program absolutely superb.
Con Too many possibilities, no unified workflow
The operations are not optimized enough for specific tasks.
Con The physics engine is a bit lagging behind, especially the destruction physics
Con Difficult learning curve
Blender has a history of being unintuitive, but the 2.8 overhaul made the program far easier for beginners to pick up, and changes continue to be made to further improve the experience. However, there is still a learning curve.
Con Not good for Industrial Design because it uses average vertex normals
You can not create a hard surface with a radius continuity degree along a surface using a specific radius value.
Con Vertex normal issues on edges after boolean operations.
After creating a simple boolean operation the vertex normals are broken. A lot of work to fix the issue and you loos surface continuity.
Con Bad vertex normal after boolean operations
Does not handle well polygon intersections. And need tweaking by hand points or adding average vertex normals via modifiers.
Con Does not handle NURBs
Is not capable of real hard surface for industrial design because is not able to reproduce surface continuity degree as a NURBs does and average vertex normal destroy surface radius.
Con Poor particle system
The Blender particle system can at times be a little limiting and finicky (and buggy) to get working. Even if it can get most straight forward jobs done, it is far from the most advanced system, and could benefit largely from advancements.
