Scala.js vs Pharo

Scala offers type inference, which, while giving the same safety as Java's type system, allows programmers to focus on the code itself, rather than on updating type annotations.

In contrast to other options, Scala.js is a compiler plugin for an already existing and mature language: Scala.
As such, it benefits automatically from the existing compiler, from the language design choices made for Scala, which exists and is established in the industry since years.

The JavaScript-interop of Scala.js is very direct and lightweight.

The strength of Scala (JVM) on the server can not be underestimated, and is probably superior to any other choice listed here (where applicable; many have no server-side equivalent).

Being able to use such a powerful language (and ecosystem) on the server AND on the client, and sharing code between the two, is a big advantage.

Scala.js implements most of the Scala standard library and many parts of the Java one. Among others, it supports Scala's rich collection library.

Scala.js performs dead-code elimination out of the box (when running in the "fullOpts" mode).

Scala supports both Functional and Object Oriented styles of programming. Beginners can learn both paradigms without having to learn a new language, and experts can switch between the two according to what best suits their needs at the time.

Keeps your client and server sources in sync.

Through SBT, Scala.js supports incremental compilation out of the box. That is: SBT automatically picks-up the changes (think "watch" in other tools) and only recompiles what is needed.

This makes the development cycle fast and very pleasant to work with.

The same good and mature tooling that can be used for Scala can be used for Scala.js out of the box (code-completion, refactoring, immediate feedback, etc.).

The immutable values make it perfect for working with concurrency.

Because Scala.js is a plugin to the Scala compiler, the whole power of the Scala language is available at compile-time. Which includes macros. Very expressive things can be done, in a type-safe way, which are difficult or impossible in other languages.

While SBT is arguably not as simple as Maven, it beats the chaos of the JavaScript build ecosystem.

In Pharo everything is an object. Compiler - object, network - object, method - also an object. And objects communicate with messages. No operators, no control-flow statements. Just objects and messages. Few things to learn, but you can learn OOP well.

There is good, free documentation including several books written by experts with extensive examples. There is an online MOOC. There are many tutorial videos. Supportive conferences and community. Even a professional support option if desired.

The nature of Pharo being a "live" environment allows you to perform live updates to your system without requiring to restart it. You can upgrade/modify classes while serving requests at the same time.

The framework for developing sophisticated web applications in Smalltalk is developed in Pharo. Seaside lets you build highly interactive web applications quickly, reusably and maintainably.

No need to search google for compact beautiful examples of how to do things, your live environment source is available and you can easily live search, see how it works and copy how the masters would do it (examples most languages still copy too).

Most languages are still copying the Smalltalk tools of yesterday - GTInspector (written in Glamorous) takes live exploration of code/running objects to a new level. It's really slick, and better yet, you can easily write your own inspectors in 10 lines of code.

Use 32 bit or 64 bit versions of Pharo on Windows, Mac & Linux.

MOOSE environment provides extensive, easily leveraged and class leading tools for code analysis and improvement.

Roassal and Mondrian provide fantastic and easily used frameworks for graphics, graphing and advanced visualisations (comparable to D3.js) but with much less code. Visualisations can be rendered into web friendly graphics (SVG, .png etc.) without additional work.