When comparing F# (via FunScript) vs PharoJS, the Slant community recommends PharoJS for most people. In the question“What are the best languages that compile to JavaScript? ” PharoJS is ranked 13th while F# (via FunScript) is ranked 36th. The most important reason people chose PharoJS is:
For people who enjoy programming in Smalltalk, Pharo allows developers to use Smalltalk for web development as well, since it transpiles Smalltalk code to JavaScript.
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Pros
Pro Easier transition from other paradigms
Since F# is not a purely functional language, it lends itself to being more easily picked up by programmers that have experience with other paradigms.
Pro Concise syntax
F#'s syntax tends to be terse while remaining very readable and easy to understand without being a chore to write.
Pro Runs on the CLR
Since F# runs on the Common Language Runtime or CLR, it has access to the entire .NET Framework, as well as libraries written in other .NET languages such as C#, VB.NET, and C++/CLI.
Pro Program the web in Smalltalk
For people who enjoy programming in Smalltalk, Pharo allows developers to use Smalltalk for web development as well, since it transpiles Smalltalk code to JavaScript.
Pro Support for Phonegap to go directly to iOS/Android mobile App
Pro Compiles to very efficient Javascript, with almost perfect Smalltalk semantics
Pro Great IDE support
Pro Seamless integration with JavaScript libraries
Can directly call to / be called from JavaScript and can use foreign JavaScript objects.
Will soon have ability to generate and use AMD modules.
Cons
Con Not really cross platform
Though the community sites are touting F# can be cross platform through use of Mono, the reality is that it is more of a hack to replay on larger mono applications in production.