When comparing ElixirScript vs Python (via Skulpt), the Slant community recommends ElixirScript for most people. In the question“What are the best languages that compile to JavaScript? ” ElixirScript is ranked 26th while Python (via Skulpt) is ranked 34th. The most important reason people chose ElixirScript is:
Uncluttered, yet unambiguous syntax
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Pros

Pro Clear syntax
Uncluttered, yet unambiguous syntax

Pro Excellent community
The Elixir community has proved to be welcoming and very supportive.
Pro Great for concurrency
Leverages the existing Erlang BEAM VM
Pro More familiar syntax
All of the benefits of Erlang; without as steep a learning curve of prolog based syntax. Elixir is heavily inspired by Ruby's syntax which many people love.
Pro Great documentation
Elixir's documentation is very good. It covers everything and always helps solving any problem you may have. It's also always available from the terminal.
Pro Suspensions
You can write blocking methods that don't cause the whole page to hang, something difficult to do in languages targeting Javascript.
Pro Interactive REPL
You can evaluate new Python code in the browser written by the user.
Cons
Con Python 2.6
Skulpt implements an outdated version of the Python language.
