When comparing HexEd.it vs 0xED, the Slant community recommends 0xED for most people. In the question“What are the best hex editors for Mac?” 0xED is ranked 1st while HexEd.it is ranked 2nd. The most important reason people chose 0xED is:
Fast editing of large files. Instant opening of files of any size. Remains responsive with 1 million+ edits.
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Pros
Pro No installation required
HexEdit.js is web-based. If you find yourself working from someone else's machine or in a web cafe this is a useful backup option, as you can access it from anywhere without installing anything, and run it regardless of that machine's OS.
Pro Responsive
Fast editing of large files. Instant opening of files of any size. Remains responsive with 1 million+ edits.
Cons
Con Depends on having a stable Internet connection
Since HexEd.it is only available online, a poor Internet connection can make this tool unusable.
Con Current version 1.14 crashes
Crashes on macOS 10.13 (High Sierra)
Con No longer updated
The website states that the app is no longer in development