When comparing TYPO3 vs Pinegrow, the Slant community recommends TYPO3 for most people. In the question“What are the best web content management systems?” TYPO3 is ranked 11th while Pinegrow is ranked 18th. The most important reason people chose TYPO3 is:
You can use both one-tree and multi-tree structure.
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Pros
Pro Flexible multi-lingual site management
You can use both one-tree and multi-tree structure.
Pro Multiple websites/domains from one installation
You can use a single TYPO3 installation for multiple websites and domains.
Pro TYPO3 is enterprise
TYPO3 can be used from small to very big installations where it is possible to give rights to users on a very fine grained basis.
Pro Realtime preview
You can see the screen preview at real time. No need to click [Preview] button.
Pro Supports top front-end frameworks
Bootstrap, Foundation, Materialize, etc. Also many other frameworks, languages, etc.
Pro Multi platform desktop software
Windows, Mac & Linux. 32 / 64 bit.
Pro Reasonably priced
Not free as the main con says, but the cost is fair; and it's okay to encourage a company that produces a quality tool at a very reasonable price.
Cons
Con Writing or debugging extension in Typoscript is a nightmare
Con Free update is available only 1 year
Update version will be available only 1 year once you buy the license.