When comparing Hardened Gentoo vs KDE Neon, the Slant community recommends KDE Neon for most people. In the question“What are the best Linux distributions for misanthropes?” KDE Neon is ranked 12th while Hardened Gentoo is ranked 36th. The most important reason people chose KDE Neon is:
Since it's built on the strong Ubuntu base, KDE Neon works seamlessly with a huge variety of hardware.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Supports custom hardened kernels
Your only real options for a widely supported hardened distro are the Red Had distros (Red Hat, CentOS, Fedora) of which Fedora is your best bet for a desktop , or Gentoo. You can make a hardened kernel in Gentoo while stripping unnecessary features, creating a much smaller attack surface, and using in-kernel mitigations others don’t.
Pro Comprehensive hardened guide in wiki
From SELinux to PaX to AppArmor to.... The wiki has got you covered.
Pro Fully customized kernel that prevents server-side malwares with SSO mechanisms
Out of CentOS /RedHat/Fedora a hardened kernel is very easy to make.
Pro Best defense against NOP-sled malwares, even with ROP/COP mechanisms
Out of CentOS/RedHat/Fedora/OpenSUSE/Slackware/FreeBSD/Mandriva and Arch, only Gentoo can best protect you against NOP-sled malwares, even with ROP/COP mechanisms.
Pro Works out of the box
Since it's built on the strong Ubuntu base, KDE Neon works seamlessly with a huge variety of hardware.
Pro Configurability
KDE Neon uses KDE as its desktop environment, which is highly configurable, but also has great defaults.
Pro The best looking Linux OS
It really is a great and stunning looking OS.
Pro Works well on low-end computers
Cons
Con Steep learning curve for beginners
It's a really sparse, bare-bones system, no automatic driver install for example. It can be quite hard for someone not used to Linux.