When comparing Hardened Gentoo vs Artix Linux, the Slant community recommends Artix Linux for most people. In the question“What are the best Linux distributions for Misanthropes?” Artix Linux is ranked 24th while Hardened Gentoo is ranked 25th.
Ranked in these QuestionsQuestion Ranking
Pro Comprehensive hardened guide in wiki
From SELinux to PaX to AppArmor to ... The wiki has got you covered.
Pro Supports custom hardened kernels
Your only real options for a widely supported hardened distro are the Red Had distros (Red Hat, CentOS, Fedora) of which Fedora is your best bet for a desktop , or Gentoo. You can make a hardened kernel in Gentoo while stripping unnecessary features, creating a much smaller attack surface, and using in-kernel mitigations others don’t.
Pro Best defense against NOP-sled malwares, even with ROP/COP mechanisms
Out of CentOS/RedHat/Fedora/OpenSUSE/Slackware/FreeBSD/Mandriva and Arch, only Gentoo can best protect you against NOP-sled malwares, even with ROP/COP mechanisms.
Pro No systemd
Pro Rolling distro
Pro Close to bare Arch Linux
No learning curve if you're coming from Arch or any of its derivatives
Only the software you would need like Terminal emulator, file manager, media player and a browser.
Artix actively supports the runit init system known from Void Linux. (Equally besides the OpenRC init system known from Gentoo.)
You can have a functional system in less than 10 mins using GUI installer OR you can do it "the Arch way"
Con Few Arch packages might not be available yet
Developers are working migrating all packages into their own repositories while ensuring there's no systemd malware.