When comparing Andy vs Docker, the Slant community recommends Docker for most people. In the question“What are the best power user tools for Windows?” Docker is ranked 43rd while Andy is ranked 70th. The most important reason people chose Docker is:
Docker creates a single object, containing an application with its dependencies, that can be moved between any docker-enabled machines, guaranteeing the same environment for application execution.
Specs
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Pros
Pro Can be rooted
To root Andy download this rootkit, extract the archive and run AndyRootkit30.exe. It comes with frequently installed root applications that can be installed in the process and also allows unrooting Andy.
Pro Easy to get started
As long as virtualization is enabled in BIOS, the setup is straightforward. Simply download, install, run. First time the software runs it will ask to either log in with a Google account or create one allowing it to download software directly from the Play Store.

Pro The virtual machine Andy runs in is highly customizable
With some tinkering, Andy can be set up to run with up to 3GB of RAM, the current Android 32bit RAM limit. It allows for a smooth experience and offers enough power to have multiple apps running simultaneously. The VM can even add more virtual CPU cores to Andy, doubling it's processing power or more.
Pro Use of Genymotion VHD allows Andy to be very fast
Andy is built on top of the powerful Genymotion VHD. It takes advantage of OpenGL capable graphics cards allowing it to be one of the fastest Android emulators.

Pro Allows installing third-party launchers
Andy comes with a custom clever implementation of ADW. It is theme-able, while functions very well without any modifications. The app sorting is a nice touch. Andy is compatible with most Android launchers.

Pro Great application compatibility and stability
Andy is constantly optimizing for applications to perform better on their system. Their support staff has a reporting setup to get the right information to the developers as fast as possible.

Pro Allows using a smartphone as a controller
It can't stream media to a phone, but it can work as a game controller. It allows for accelerometer- and touch-based interactions.

Pro Good customer support
Andy manages support mostly through a Facebook group where both knowledgeable admins and smart community members help answer questions.

Pro Fully functioning notifications and widgets
Andy supports all traditional Android widgets and notifications. It can even use apps like Push Bullet to send those notifications to their other devices.

Pro Great Clash of Clans gameplay experience
The new launcher provided for, it seems, limitless number of Andy tablets. Have a Andy just for CoC with 3GB and 4CPUs to maximize your CoC play to the next level. Then make a full copy of that machine for a full backup. Have an Andy for the children, be able to lock each Andy with a password lock-screen. And manage all this with less only 7 buttons ;) Again, Simple and powerful.

Pro Simple OS upgrade process
As of this latest version, users can be notified of new versions and incremental changes. It's possible to update only certain pieces or parts, rather than downloading an entirely new build. Andy is also exploring OTA update possibilities.
Pro Andy is available in over 40 languages.
For a full list of supported languages, see here.

Pro All apps and settings can be synced between Andy and an Android device on the same network with 1ClickSync
While setting up Andy, 1ClickSync will ask for Google Account credentials that allow keeping apps and their settings in sync between Andy and an Android device.

Pro Available on Windows 7 & 8
Andy is available on Windows 7 and 8.1 PCs with OS X support in development.
Pro No signup required
Downloading Andy requires only one click with no email address or account needed.
Pro Allows for portable application deployment
Docker creates a single object, containing an application with its dependencies, that can be moved between any docker-enabled machines, guaranteeing the same environment for application execution.
Pro Git-like capabilities
Docker tracks changes in systems. It allows for commits and rollbacks and for quick deployment due to having to deploy only the updated code.
Pro Allows re-using components
Docker essentially allows creating boilerplate systems (a LAMP stack, for example) that can be used as a starting point on multiple projects. And you can find multiple such containers already created by people in their public registry.
Pro Automatic build
Allows automatically assembling a container from its source code.
Pro Provides easy sharing and installation of containers through a public registry
Docker allows easily pushing and pulling containers to and from their public index.docker.io registry. Additionally, dotCloud maintains a list of official repositories of the more popular containers.
Pro Application-centric
Pro Works in virtualized environments
You can set up Docker within an already virtualized environment such as a virtual machine. This allows you to run Docker on Mac and Windows, among other use-cases.
Pro Low overhead
Pro Supports a wide range of isolation tools
Docker can be used with OpenVZ, systemd-nspawn, libvirt-lxc, libvirt-sandbox, qemu/kvm, BSD Jails, Solaris Zones, and chroot.
Pro Tool ecosystem
Cons
Con Andy's Installer is known to drop/install a bitcoin miner
Andy's Installer has been reported to drop a bitcoin miner on users computer which causes significant drop in PC performance.

Con Still on Jelly Bean
KitKat version is planned.
Con No Linux Version
Con Can crash your mac
Con Only installs in Windows Drive C:/
Which is where windows is installed. What's more, it does not let you change the installation path.
Con Quite resource intensive
Con Large image size
Con Security concerns
Con Kernel OS fragmentation
