When comparing Sencha Touch vs Intel's App Framework, the Slant community recommends Sencha Touch for most people. In the question“What are the best frameworks for developing cross-platform mobile apps with JavaScript?” Sencha Touch is ranked 15th while Intel's App Framework is ranked 19th. The most important reason people chose Sencha Touch is:
Sencha Touch is well known for its ability to provide a native app experience through it's native-like themes and widgets.
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Pros
Pro Native feel
Sencha Touch is well known for its ability to provide a native app experience through it's native-like themes and widgets.
Pro Detailed documentation
Sencha provides exhaustive documentation that covers all aspects of developing with their products.
They also provide a well written getting started guide that's easy to follow.
Pro Lightweight
Intel's App Framework is built to be lightweight and fast.

Pro Supports variety of platforms
Intel's App Framework allows you to build apps for just about any platform. iOS, Android, Windows 8, Tizen, Amazon, Nook, Chrome & Firefox.
Cons
Con Commercial and expensive
Sencha Touch is targeted towards enterprise-level development, and the price tag reflects that.
There are many different product options available by Sencha. Most licenses start in the thousands of dollars, and require a minimum purchase of 5.
Con Weak documentation
The documentation for the app framework is fairly basic, with a limited number of descriptions/explanations given.
