Virtual Box vs F.lux
When comparing Virtual Box vs F.lux, the Slant community recommends F.lux for most people. In the question“What are the best Mac OSX apps for someone that's new to Apple?” F.lux is ranked 5th while Virtual Box is ranked 15th. The most important reason people chose F.lux is:
Helps provide better sleep for more energy during the day.
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Pros
Pro Compatible with Many Operating Systems
It works for Windows, macOS, Linux, BSD, and many others.
Pro Beginner friendly
A virtual machine can be set up in minutes if a ISO file to load is already available.
Pro Works well and fast for Windows host and Linux guest
Pro Free and open source
Pro Many free images available
Though most are linux flavors at https://virtualboxes.org/
Oracle's virtualbox site has others.
Pro Can do snapshots
Pro A lot of customization
VirtualBox has multiple virtualization options. Each one may be tailored to the guest operating system’s needs. This makes it especially good on virtualizing older systems, such as DOS, obscure distros, etc.
Pro Can help sleep better
Helps provide better sleep for more energy during the day.
Pro Eases eye strain
Decreases color temperature at night, changing the normally fluorescent blue of an LCD monitor to a soft orange. Much easier on the eyes, especially in a low-light environment.
Pro Subtle transition
The transition from daytime to nighttime color modes takes an hour by default and will detect your current timezone, meaning that it will happen in the background at sunset, often without you noticing.
Cons
Con Lacks video performance
Virtualbox has a hard cap of 256MB of video memory. This could make newer operating systems run slower.
Con Minimal CPU customization
You can only enable/disable certain features. You cannot cap the speed of the CPU, which is required to run systems such as Windows 95.
Con Takes a while to get used to
After installing F.lux, the screen will look a lot more yellow. This takes about a week to fully get used to. You can ease into it by setting the color temps higher than the recommended defaults.