When comparing TrueCrypt vs Disk Utility, the Slant community recommends Disk Utility for most people. In the question“What are the best file encryption tools?” Disk Utility is ranked 11th while TrueCrypt is ranked 20th. The most important reason people chose Disk Utility is:
It offers the best integration, ease of use and support with OS X.
Ranked in these QuestionsQuestion Ranking
Pros
Pro Can encrypt entire disks
Other than volumes and folders, TrueCrypt can encrypt whole disks too, including the system disk.
Pro Native OS X support
It offers the best integration, ease of use and support with OS X.
Pro Disk image and volume encryption
You can create a disk image that requires a password to mount. It can use a different filesystem than OS X, like exFAT, that can be used to move files between Windows and OS X. Additionally, you can encrypt file volumes by right-clicking and selecting encrypt.
Cons
Con Abandoned
As of May 28th, TrueCrypt is abandonware. The website warns that using the software might not be secure and suggests moving to BitLocker. The source code is available and there are rumors of an official fork.
Con Mac only
Disk Utility is available for OSX only.