When comparing Exim vs Qmail, the Slant community recommends Exim for most people. In the question“What are the best Linux mail transfer agents (MTAs)?” Exim is ranked 1st while Qmail is ranked 4th. The most important reason people chose Exim is:
Most Linux distributions that come with Exim, come with sane Exim default configurations. Changing default values and slightly adjusting configuration is relatively easy. On the other hand, building a completely new Exim configuration file from scratch might not.
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Pros
Pro Easy to use
Most Linux distributions that come with Exim, come with sane Exim default configurations. Changing default values and slightly adjusting configuration is relatively easy. On the other hand, building a completely new Exim configuration file from scratch might not.
Pro Good documentation
Exim provides thorough documentation with great examples.
Pro Sendmail compatible
Exim is a drop-in replacement for Sendmail.
Pro Excellent security
Qmail was built ground up with security in mind.
Pro Fast
Qmail parallelizes mail delivery to increase speed.
Pro Easy to maintain
Configuration of Qmail is sane and straightforward.
Pro Sendmail compatible
Qmail is a drop-in replacement for Sendmail.
Cons
Con Missing some features
Missing featues like: webmail, ActiveSync, WebAdmin.
Con No support for some protocols
No support for: POP3, IMAP, POP3s (POP3 over SSL).
Con Unsupported
The original author of Qmail stopped maintaining it in 1998. It was released to public domain in November 2007.