When comparing Bootstrap vs Inkscape, the Slant community recommends Inkscape for most people. In the question“What are the best web design tools?” Inkscape is ranked 7th while Bootstrap is ranked 12th. The most important reason people chose Inkscape is:
Inkscape is GPL-licensed and maintains public repositories.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Consistency across browsers
The grid layout with the predefined CSS elements and JavaScript components make it easier to have consistency across different browser versions and even different devices.
Pro Responsive design philosophy
Bootstrap is developed to be instantly compatible with all sizes of screens, so you don't have to worry about which device the user is accessing your site from. Yet if you prefer, you can disable responsiveness of Bootstrap.
Pro Well documented
Documentation is thorough, well organized and full of live examples and templates ready for use. Every component and every part of the framework is explained and covered in depth.

Pro Custom builds
If you don't want to download the full Bootstrap framework. Custom builds of Bootstrap can be created, including only the desired CSS, CSS components, and JavaScript components. This can be done directly from the Bootstrap website by simply choosing what components to download.
Pro Designed to get a site running quickly
Bootstrap is designed to get a site up and running quickly. Each of it's components is pre-configured to help with getting a site up and running quickly.
Pro Great community
Bootstrap is very popular and has a large community. As a result of this it is much easier to find help with anything you might need. This also gives you a treasure trove of prebuilt components to use and add to your site.
Pro Supports responsive embeds
Allows easily adding responsiveness to <iframe>
, <embed>
, and <object>
elements.
Pro Easily make professional looking websites
Bootstrap makes it easy to learn how to make professional looking websites. It can even make code junkies semi-enjoy design.
Pro Customizable
Bootstrap can be customized in a variety of ways. Either by overriding the default CSS styles with new CSS styles or by editing the .scss
Bootstrap files.
Pro A wide variety of themes available
To help you avoid the "Bootstrap look", there are many resources that provide a great selection of themes and templates for Bootstrap.
Pro One of the most popular ones
Ranked on GitHub as the most starred CSS repository.

Pro Free and open source
Inkscape is GPL-licensed and maintains public repositories.

Pro Opens lots of file types
Inkscape supports many common formats for import (including SVG, Photoshop and Illustrator) and its plugin architecture allows more to be added.
Pro Export to different file types
Files can be exported and saved as a "normal" svg, png, jpg, bmp etc. file.

Pro Cross-platform
Pre-built binaries are available for Windows, Mac and Linux. Inkscape can be built from source on additional platforms.
Pro Integrates well into a X11-System
Its uses the X11 icon theme and desktop theme(GTK).
Pro It can do anything
A very powerful software that can do pretty match anything!
Pro Measurement Tool
This tool is extremely handy and can not be found in any other vector graphics programs out there.
Pro Live Path Effects
Extremely powerful menu that offers more than 30 powerful Live Path Effects to apply to paths vastly enhancing the application functionality.
Pro Guides, Grids, and Canvas Rotation
Extremely handy features when building complex graphics using Inkscape.
Pro Dark Theme Support
The new 1.0 beta 2 version finally got support for dark theme which normally is only available for commercial software like Affinity Serif, Adobe Illustrator.
Pro The new version 1.1 is looks and feels fantastic
Inskape got UI update: new dockable dialogs.
Pro Interface is available in 29 languages
Basque, British English, Brazilian, Portuguese, Catalan, Croatian, Czech, Dutch, Finnish, French, German, Greek, Hindi, Hungarian, Icelandic, Indonesian, Italian, Korean, Latvian, Norwegian (Bokmål), Polish, Romanian, Russian, Slovak, Spanish, Swedish, Turkish, Ukrainian, Urdu, Swedish.
Pro It's really easy and fun
Vector graphics can be created and edited with Inkscape.
Cons
Con Large file size out of the box
Bootstrap has an out-of-the box filesize of ~276K, which is pretty large considering it's just CSS. Most of those styles aren't even used in 90% of web pages built with Bootstrap. By only including the required styles it can be trimmed by 70%-75%.
Con Too many classes
Bootstrap's over-reliance on HTML classes for styling can get very messy very quickly. There's also an overabundance of DOM elements which have a lot of classes and are more often than not nested inside DOM elements with even more classes. This gets problematic down the line because the maintainability of the project gets harder when the project starts to get large.
Con Websites can start to look the same
If the initial Bootstrap colors and styles are not changed or edited, different websites start looking the same even if they have nothing to do with each other and they are made by different developers.
Con Hard to customise
It's quite hard to customise Bootstrap using pre-processors like SASS and LESS, the only real flexibility is with typography and colours.
Con Large font sizes

Con Very slow startup on some systems
Depending on factors like how many fonts you have installed, Inkscape can take upwards of 30 seconds to launch.
Con Uses its own SVG-format by default
Inkscape might use SVG as its default format, however this SVG's contains some additional SodiPodi/Inkscape additions that can be troublesome if you want to import the SVG into some other application.
Con 1.0 is sluggish
Inkscape 1.0 uses GTK 3 which is sluggish and slow for low spec systems( eg. ARM, Celeron, Pentium, Core-i3, Ryzen 3 or Athlon ) compared to previous versions.
Con Buggy
Application is often buggy so it happens from time to time that the popup / right-click menu won't close and stays open. It crashes also sometimes randomly. This makes it almost unusable for productive / business use.
Con Crashes very often
Inkscape encountered an internal error and will close now - is one of its standard messages.
Con Since 0.91 the gradient editor is gone
It is now only possible to edit a gradient on screen. but you can't set a stop to a specific percentage anymore.
Con Limited work with ICC CMYK color scheme
Support for ICC color profiles only in SVG files.
Con Uses GTK
It looks an feels like an alien. It also uses now touch-based widgets instead of professional widgets.
Con Y-axis inverted
0,0 coordinates begin in lower left corner, not upper left corner as SVG standards define in Inkscape 0.92.x.
It seems this is now fixed in the 1.0 beta 2 version of the program.
Con A toy for facebook-ist enthusiasts, not for professionals
It's a Linux niche mumbo-jumbo, same as GIMP for raster edit .
Con Based on the GTK widget toolkit
Software is based on GTK, so it might not integrate well in non-GTK environments. It also requires many dependencies on those non-GTK desktops. It also adds dependencies to GTK-environments since it is written in C++ which requires the gtkmm wrapper/interface.
Con Mac version does not look as polished as its versions for Windows/Linux version for the 0.92.x version
It seems that Inkscape 1.0 beta 2 for Mac got some needed attention and it looks a lot better with dark theme support. native DMG installer and they got rid of X11 which is great.
Con Incompatible with previous versions
Sometimes backward compatibility breaks. For example, pre 0.92 SVGs are incompatible with later releases (due different default resolutions).
Con No support for large printing machine system
No support for large printing machine environment, except exporting the resulting artwork to PDF.
Con Under GNU GPL
It is released under GNU GPL which one of the restricted open source license.
