When comparing Skeleton vs Spectre, the Slant community recommends Skeleton for most people. In the question“What is the best CSS framework?” Skeleton is ranked 5th while Spectre is ranked 11th.
Ranked in these QuestionsQuestion Ranking
Pro Responsive grid
Pro Style agnostic
Pro Vanilla CSS
No bells and whistles for Skeleton, it's just CSS.
Pro Media queries
Pro Mobile ready
Spectre can be used to create mobile websites easily. With all the regular built in elements (buttons, menus, grids etc).
Works well on any device.
Pro Open source
Spectre is used through Github, and is open source.
Contains only the basics, no extra fluff.
Very clean design compared to bootstrap.
Con Not maintained anymore
No active development for two years.