When comparing Skeleton vs Blueprint, the Slant community recommends Skeleton for most people. In the question“What is the best CSS framework?” Skeleton is ranked 6th while Blueprint is ranked 37th.
Ranked in these QuestionsQuestion Ranking
Pro Responsive grid
Pro Style agnostic
Pro Vanilla CSS
No bells and whistles for Skeleton, it's just CSS.
Pro Media queries
Con Not maintained anymore
No active development for two years.
Con No preprocessor support
No support for Sass, Less, or Stylus.
Does not follow the responsive web development philosophy.
It was last updated in 2011.