When comparing Google Chrome vs LessPass, the Slant community recommends LessPass for most people. In the question“What is the best cross-platform password manager?” LessPass is ranked 14th while Google Chrome is ranked 20th. The most important reason people chose LessPass is:
Works everywhere, in any device that can run javascript.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Syncs between devices
By logging into Chrome using a Google account it's possible to sync history, extensions, passwords, bookmarks and other settings between devices. This makes it great for anyone working with multiple devices as it allows experiencing consistent context when in the browser.

Pro Excellent HTML 5 feature support
As of February 2015, Chrome scores highest of all browsers for HTML5 compatibility.

Pro Installs extensions without requiring a restart
Pro Great built-in developer tools
Chrome comes with built-in developer tools, making testing and enhancing web pages simpler for those of us involved in working with such technologies. As well as being beneficial to developers, this also has some benefit to non-technical users; in that by making testing simpler for developers those developers are more likely to use Chrome for their tests, and can spend more time making improvements over investigating underlying causes of issues.
Pro Good performance
According to TopTen Reviews, Chrome is currently one of the best performing browsers for initial (cold) startup, average startup, and navigation times.
Pro Backed and supported by Google
Whilst Chrome is based on the open source browser Chromium), Google reviews this code and build on top of it. This means it takes (and contributes to) a number of the benefits of the open source model whilst having the resources, support and investment of a major company.
Pro Plenty of extensions
Pro Automatically updates
Chrome updates in the background ensuring you're always on the latest version. This makes it much more likely that sites will work on your browser, since (almost) all Chrome users will be running exactly the same version.
Pro Simple user interface
For example, the address bar is also the search bar. Google calls it Omnibox.
Pro Multiple account login
You can have multiple Chromes with different accounts logged at the same time. And it is really easy to manage different accounts.
Pro Huge variety of extensions available
Pro Customizable by user
Each of the managed users can have their own configuration (themes, extensions, ...)
Pro Popular
As of March 2015, Chrome is the most popular browser on the internet, with a 43.9% - 63.7% market share, meaning most developers will be testing their sites against this browser to ensure compatibility.
Pro Sandboxed Tabs
Every tab runs as their own process, so if one crashes or becomes unresponsive, the whole browser isn't affected.
Pro Uses Blink
It uses the blink rendering engine which has removed many legacy khtml/webkit code to be much lighter and faster.
Pro Really platform-free
Works everywhere, in any device that can run javascript.
Pro Doesn't store passwords
If it's not stored, it can't be stolen.
Pro Open source
Cons
Con Huge memory hog
Each tab and extension in the browser uses significant chunks of RAM, giving the browser poor performance on machines without enough RAM to supply.
Con Gives too much weight to Google on the future of the Web
Con Online tracking by default
Chrome allows opting out of tracking by going to Settings > Advanced > Privacy and un-checking any unwanted services. Alternatively Chromium can be used to get a similar browser experience without Google's services on top of it.
Con Increasingly slow
When Chrome first came out, it was known for being lightweight and very speedy. Over the years, more and more features have been added to Chrome. Because of this, crashes, errors, and general laggy-ness has increased noticeably.
Con Bad for battery life
Drains battery life on both Windows laptops and Macs much quicker than the alternatives. It can shave hours off the battery life of any non Chromebook laptop.
Con Proprietary
Google Chrome is proprietary software, meaning that it is not open source.

Con Blurred fonts on Windows
Fonts on Windows are blurred, that is especially noticeable in light fonts on dark background. Small italic text is hard to read.
Con Hard/impossible to transfer passwords to a different machine without uploading them to Google
Con Does not hardware accelerate HTML5 video correctly
Chrome is unable to hardware accelerate HTML5 video correctly which makes playing 4k video on laptops a poor experience filled with lag.
Though there is a workaround for YouTube in that a plugin can be installed to force Flash playback instead of HTML5, which plays smoothly and has no HW acceleration issues. There's another plugin (h264ify) that will force to use the h.264 codec video if available instead of the VP9 one which is the resource hog.
Con No mobile extensions
Chrome on Android and iOS does not support extensions.
Con Basic
Unlike Opera and Vivaldi which are more stable and has more features, Chrome is pretty basic.
Con Bad quality control on extensions
Some just plain don't work while a few actually break the browser.
Con Easily cracked with exposed/compromised master password
Since anyone can use LessPass with the same parameters as you, all they need is your master password (which could be obtained through keylogging or numerous other methods) to gain access to every one of your site passwords.
Con Cannot store existing secrets
Existing secrets (aka passwords) cannot be stored with deterministic password managers. In order to use LessPass effectively, you will need to change your password on every site.
Con Deterministic
Deterministic password managers have many drawbacks.