When comparing Enso Portable vs MobaXterm, the Slant community recommends MobaXterm for most people. In the question“What are the best power user tools for Windows?” MobaXterm is ranked 27th while Enso Portable is ranked 50th. The most important reason people chose MobaXterm is:
MobaXterm can connect to practically anything.
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Pros
Pro Extensible in Python
GChristensen recently upgraded Enso to Python 3.7, a great improvement over the original v2.5. You can write custom Enso commands in Python through its new web interface (or your favorite editor once you know where to put the files.) There's even an install command to pip install any Python package you need from PyPI. The sky's the limit.
Pro Optional quasimode
Letting go of CapsLock just feels faster than hitting enter (sometimes too fast: be sure to disable the reboot command before turning this on!) Even with quasimode enabled, you can make it modal for that command by tapping Alt.
Pro Easily teach the app to open specific apps and sites
There is a learning function to the app that allows the user to teach the app to open specific items by typing "learn as open" and then clicking on the item one wants it to learn to open.
Pro Can go to existing open windows
By using the "go" command users can switch to their already open windows making this a bit of a window navigator as well as a launcher.
Pro Flexible
MobaXterm can connect to practically anything.
Pro X server support
In case you need X11 forwarding, MobaXterm has an integrated X server.

Pro Full linux subsystem with package manager
And you can install conda for additional package management.
Pro Tabbed or split mode
Multiple terminals can either be in tabs or split horizontally or vertically.

Pro Integral remote file editor
Edit remote files via ssh and sftp
Pro SSH tunnel controls and forwarding UI controls makes it easy
Pro Automatic SFTP
With MobaXterm, there's no fiddling with multiple apps: simply connect and everything is available.
Pro Connection manager
Pro ENV can use Windows PATH
Pro Password vault
Pro Server tools (HTTPD, SSHD, SFTPD, TTFT)

Pro Build in sftp file manager
Manipulate and edit remote files in the file browser.

Pro Integrates with WSL
Integrates perfectly with the Windows Subsystem for Linux. Out of the box it offers a shell to that system.
Pro Supports macro controls (multi commands in single screen)
Cons
Con Comes with a reboot command
And a shutdown command too. Installing these is optional, and I recommend that you don't, especially if you use the quasimode. Unless you like losing your work.
Con No message log
According to Raskin's philosophy which inspired Enso, a pop up "dialog" is a bad design. The OK button is a useless input that interrupts your flow. Enso's pop up messages, therefore, are transparent and quickly fade away on their own (like Android Toast messages). Unfortunately, this also means you can easily miss them if you're not paying attention. Raskin's solution was to keep a message log you can refer back to, but Humanized never got around to implementing that for Enso.
Con Usage tends to be slowed by the caps lock
Function of the app relies on the caps lock key being pressed to enter commands, which can slow some people down by having to hold that key down when they are typing commands.
Con Not completely freeware
If you use MobaXterm at work, they hope you will pay for it. This isn't horrifying, but it's not providing any new features in Linux to warrant the outlay. Its integration with Putty in Windows as an X client may make it worth the funds.
Con Split screen prevents tabbed mode
If you split a screen within a tab, you have to go back to single screen before you can switch to another tab.
Con Can have some performance issues
MobaXterm can have some occasional performance issues. These happen rarely but it's worth mentioning that they exist, especially since this is a paid tool.
