When comparing Pyxel Edit vs GrafX2, the Slant community recommends GrafX2 for most people. In the question“What are the best pixel art / sprite editors?” GrafX2 is ranked 3rd while Pyxel Edit is ranked 5th. The most important reason people chose GrafX2 is:
GrafX2 is scriptable using the Lua language, which can be used to automate tasks and add new functionality to it. The script library features advanced color reduction and enhancement tools, [palette analysis](http://eab.abime.net/showthread.php?t=76519), and much more.
Ranked in these QuestionsQuestion Ranking
Pro Intuitive UI
Pyxel Edit is widely acclaimed for its ease of use.
Pro Supports animations
Tiles can be animated within Pyxel Edit, with "onion skin" frame overlays to assist in making smooth frame transitions.
Pro Tileset extraction
Given an image and specified tile dimensions, Pyxel Edit will extract a tileset with no duplicate tiles. This mostly works for flat images though. If you feed Pyxel "finished maps" you will still get a lot of duplicates.
Pro Tilemap serialization support
Tile-based images (maps) built in Pyxel Edit can be serialized via XML or JSON for easy import elsewhere.
Pro Cheap compared to others
For only $9 (£6), this is one of the cheapest but also one of the best pixel editors out there.
Pro Live tile-update
Instantly see if your tiles are tileable and/or seamless and fix it easily.
Pro Indexed tiles can be used for reusing objects in animations
Pro Scriptable using Lua
GrafX2 is scriptable using the Lua language, which can be used to automate tasks and add new functionality to it. The script library features advanced color reduction and enhancement tools, palette analysis, and much more.
Pro Supports many file formats
GrafX2 supports many file formats, including the popular gif and png, but also importing and exporting from deluxe paint, degas elite, and various other editors using custom formats.
Pro Palette color cycling
GraphX2 being based on older 256 bitmap software has inherited some tricks that modern pixel editors do not have . One of them being the ability to cycle color palette and produce animations and effects with it.
Pro Free, open source, and cross-platform
GrafX2 is totally free to use, copy, and modify. It's available on Windows, Linux, Mac OS X, Haiku, AROS, MorphOS, SkyOS, Syllable, Mint, and a few more systems. Basically anything is supported by the SDL library.
Pro Very large number of tools and effects
Pro Supports tileset addition and extraction
Pro Has a great palette tool
You can create gradients from one color to another, work in either RGB or HSL color space, save and load palettes, sort and organize palettes, and even work on "color cycling" images.
Pro Supports animations
The program has a basic support for animation using frames in newer versions. Graphics can be cloned and copied between frames and changed slightly.
See here how to animate with GrapfX2 https://www.youtube.com/watch?v=Gnq6zBZOqoM
Pro Has a customizable UI with themes support
Theme UI style can easily be changed from settings including buttons and colors.
Pro Drawing constraint mode for vintage 8bits machine
The program is able to enforce the pixel constraints of old machines (C64, ZX Spectrum, Apple II, Game Boy Color, etc.)
For example, in ZX Spectrum mode, only 2 different colors can be used in a 8x8 pixel block.
Con No Linux version
There is no Linux version of the editor.
Con Free version lacks features
The free version of Pyxel Edit is an outdated beta. It does not receive updates.
Con Proprietary, closed-source software
This software does not respect your freedom.
Con Mac version is dependent on Adobe Air
The OSX version of the application requires Adobe Air to run.
Con Lacks some tools
Con Dated look and feel
It looks like it was never supposed to be used in the modern world.
Con Lack of modern features
Some modern features that are necessary to do pixel art creation for game dev work are lacking.