When comparing Pyxel Edit vs Aseprite, the Slant community recommends Aseprite for most people. In the question“What are the best pixel art / sprite editors?” Aseprite is ranked 1st while Pyxel Edit is ranked 6th. The most important reason people chose Aseprite is:
You can change the playback speed of the loop and the speed of each individual frame. There are three playback modes: forward, reverse, and ping-pong. Onion Skin mode is included to speed up the animation process and to allow for tagging the timeline to help keep animations organized. There is also a live preview so you can always see the end result. Onion Skin mode will overlay previous and next frames over the canvas so you can use them as references when drawing. For Onion Skin mode, you can adjust items like range, opacity, and tint, whether the onion frames are in front of or behind the canvas, etc. You can tag different parts of the timeline when, for example, you need different animations for the same character. You can then loop those tagged sections individually.
Specs
Ranked in these QuestionsQuestion Ranking
Pros
Pro Supports animations
Tiles can be animated within Pyxel Edit, with "onion skin" frame overlays to assist in making smooth frame transitions.
Pro Intuitive UI
Pyxel Edit is widely acclaimed for its ease of use.
Pro Tileset extraction
Given an image and specified tile dimensions, Pyxel Edit will extract a tileset with no duplicate tiles. This mostly works for flat images though. If you feed Pyxel "finished maps" you will still get a lot of duplicates.
Pro Tilemap serialization support
Tile-based images (maps) built in Pyxel Edit can be serialized via XML or JSON for easy import elsewhere.
Pro Cheap compared to others
For only $9 (£6), this is one of the cheapest but also one of the best pixel editors out there.
Pro Live tile-update
Instantly see if your tiles are tileable and/or seamless and fix it easily.
Pro Indexed tiles can be used for reusing objects in animations
Pro Good selection of tools for animation
You can change the playback speed of the loop and the speed of each individual frame. There are three playback modes: forward, reverse, and ping-pong. Onion Skin mode is included to speed up the animation process and to allow for tagging the timeline to help keep animations organized. There is also a live preview so you can always see the end result.
Onion Skin mode will overlay previous and next frames over the canvas so you can use them as references when drawing. For Onion Skin mode, you can adjust items like range, opacity, and tint, whether the onion frames are in front of or behind the canvas, etc.
You can tag different parts of the timeline when, for example, you need different animations for the same character. You can then loop those tagged sections individually.
Pro Easy to use
Getting started with the program is straightforward. It's laid out intuitively: the main workspace in the middle, color selection on the left, tool section on the right, and animation timeline at the bottom.
All tools and the vast majority of functions have keyboard shortcuts, allowing for results to be obtained quickly.
Aseprite is a very focused program: it's not filled with icons, there's no excess functionality, and dialog boxes generally only have a couple of options so you're never overwhelmed and it's easier to learn.
Pro Responsive developer
Always in touch with the community and approachable via Twitter.
Pro Awesome tools
Tools are good, easy to use.
Pro Pixel perfect mode
It makes drawing lines and shapes less jaggy by default.
Pro Free and paid versions available
Aseprite is free if you compile it yourself. Its maintainers also offer a security-signed package with a technical support license for a one time fee of $14.99. It's also easy to use and presents really awesome tools.
Pro Cross-platform
Aseprite is available on macOS, Windows and Linux. The unfree source code is published on GitHub.
Pro Made for pixel art
It was designed with pixel art in mind, unlike other general-purpose image editors. This means you get lots of useful features and very little clutter from tools and features that you won't need.
Pro Very intuitive thus easy for complete beginners
The interface invites you to be creative, and since it's pixel art you are creating, this adds to the feeling of being in the right environment. Everything seems to have its natural place and thereby could make beginners feel right at home.
Pro Beautiful interface
Aseprite has a beautiful pixel-art interface that makes it a pleasure to use.
Pro Scriptable using Lua
Aseprite is scriptable using the Lua language, which can be used to automate tasks and add new functionality. Some consider the API more user-friendly than GrafX2's.
Cons
Con development has stopped -- developer has stated 8/20 that a new version will be released soon
Con Lacks some tools
Con No Linux version
There is no Linux version of the editor.
Con Free version lacks features
The free version of Pyxel Edit is an outdated beta. It does not receive updates.
Con Proprietary, closed-source software
This software does not respect your freedom.
Con Mac version is dependent on Adobe Air
The OSX version of the application requires Adobe Air to run.
Con Not FLOSS anymore
The license was changed to a shared license, that does not allow redistribution of the source code. While older versions should still be FLOSS, the newest versions are not.
Con Text tool could be better
You can't change text and its font or size after you've inserted it. You have to re-insert text every time you wish to make an edit.
Con No tilemap support yet
A tilemap editor is on the roadmap for version 1.6.
Con Pixel-styled interface can be jarring
Aseprite uses low-resolution window frames and fonts. Opinions vary on whether this sets the mood or gets in the way.