Here’s the Deal
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When comparing PikoPixel vs Hexels 2, the Slant community recommends Hexels 2 for most people. In the question“What are the best pixel art / sprite editors?” Hexels 2 is ranked 12th while PikoPixel is ranked 19th. The most important reason people chose Hexels 2 is:
The interface of Hexels 2 makes it easy to fluently draw isometric pixel-arts and simple 3D drawings.
Specs
PlatformsMac, Linux, BSD
LicenseAGPL3+
PlatformsWindows; OSX
Ranked in these QuestionsQuestion Ranking
Common Questions
Pros
Pro Customizable canvas background
You can change the canvas background to a different texture and color, while you can also adjust the texture size.
Pro Neat interface
The interface of Hexels 2 makes it easy to fluently draw isometric pixel-arts and simple 3D drawings.
Cons
Con Not available on Windows
PikoPixel is only available for Mac and Linux.
Con Quite expensive
Costs $38, there is a free trial available.